Cross-Round Aggregation in Interactive Whole-Body PET/CT Lesion Segmentation: a Training-Free Study Alongside a Baseline Submission to autoPET V

autoPET V scores interactive whole-body PET/CT lesion segmentationby the area under the Dice-versus-interaction-round curve, so thetrajectory across rounds matters as much as the final state. Wesubmit the organisers’ nnU-Net interactive baseline withoutmodification, and report alongside it an offline study of training-freestrategies that reuse predictions from earlier interaction rounds. Onthe single worked example released with the challenge repository, arunning union of predictions across rounds raises the AUC of Dicefrom 3.5141 to 3.5484 and converts a non-monotone Dice trajectoryinto a monotone one, which is precisely what an area-under-curvemetric rewards. Every tightening or smoothing aggregate we testedwas worse than the union, and one apparently reasonable variant —deleting whole connected components touched by a backgroundscribble — was catastrophic (AUC 2.7795), because underaccumulation the lesion region merges into a single largecomponent. Decomposing the union’s residual error shows that 78.6 % of it consists of voxels the model never predicted in any round,which bounds what any inference-time aggregation can achieve andis our reason for not carrying this into the submission. All numberscome from one case, one scribble strategy and one tracer; they arereported as a hypothesis-generating observation, not as a validatedresult.

Authors

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-08-28
DOI
https://doi.org/10.5281/zenodo.22148619
Primary Topic
Medical Imaging Techniques and Applications
Type
preprint
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
preprint

Cross-Round Aggregation in Interactive Whole-Body PET/CT Lesion Segmentation: a Training-Free Study Alongside a Baseline Submission to autoPET V

Yen-Hsiang Wang
Zenodo (CERN European Organization for Nuclear Research)
Medical Imaging Techniques and Applications
preprint

Cross-Round Aggregation in Interactive Whole-Body PET/CT Lesion Segmentation: a Training-Free Study Alongside a Baseline Submission to autoPET V

Yen-Hsiang Wang
preprint en

Abstract

autoPET V scores interactive whole-body PET/CT lesion segmentationby the area under the Dice-versus-interaction-round curve, so thetrajectory across rounds matters as much as the final state. Wesubmit the organisers’ nnU-Net interactive baseline withoutmodification, and report alongside it an offline study of training-freestrategies that reuse predictions from earlier interaction rounds. Onthe single worked example released with the challenge repository, arunning union of predictions across rounds raises the AUC of Dicefrom 3.5141 to 3.5484 and converts a non-monotone Dice trajectoryinto a monotone one, which is precisely what an area-under-curvemetric rewards. Every tightening or smoothing aggregate we testedwas worse than the union, and one apparently reasonable variant —deleting whole connected components touched by a backgroundscribble — was catastrophic (AUC 2.7795), because underaccumulation the lesion region merges into a single largecomponent. Decomposing the union’s residual error shows that 78.6 % of it consists of voxels the model never predicted in any round,which bounds what any inference-time aggregation can achieve andis our reason for not carrying this into the submission. All numberscome from one case, one scribble strategy and one tracer; they arereported as a hypothesis-generating observation, not as a validatedresult.

Zenodo (CERN European Organization for Nuclear Research)
Taipei Medical University (TW)
Medical Imaging Techniques and Applications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Cross-Round Aggregation in Interactive Whole-Body PET/CT Lesion Segmentation: a Training-Free Study Alongside a Baseline Submission to autoPET V — Yen-Hsiang Wang · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS