Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Authors
- Roshan Kumar Mahato (ORCID: https://orcid.org/0009-0009-9434-1650)
- Muhammad Hassaan Javaid (ORCID: https://orcid.org/0009-0000-1800-1800)
- Ayesha Ahmad (ORCID: https://orcid.org/0000-0003-2324-158X)
- Muhammad Ajmal Khamosh
- Amna Ahmad
Institutions
- Liaquat University of Medical & Health Sciences (PK)
- Sylhet MAG Osmani Medical College (BD)
- Khyber Medical University (PK)
- Shifa International Hospital (PK)
- University College of Islamabad (PK)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2026-08-26
- DOI
- https://doi.org/10.1002/ccr3.73335
- Primary Topic
- Hypothalamic control of reproductive hormones
- Type
- article
- Field-Weighted Citation Impact
- 0.00