Early onset schizophrenia may have aberrant brain network compared to adult‐onset schizophrenia

are included in developmental monitoring resources from the US Centers for Disease Control and Prevention's Learn the Signs Act Early program and the American Academy of Pediatrics' Bright Futures guidelines."Because children with autism and other DD are likely to struggle with daily skills in adolescence, any way to identify them early to provide support to promote independence would be helpful, the researchers wrote."Future investigations are needed to explore whether services and supports to boost expressive language and fine motor skills and reduce attention problems in children with autism and other DD can improve acquisition of DLS and promote greater independence in adolescence." LimitationsThe researchers detailed the following limitations: • Reliance on a caregiver-reported measure of DLS, which may underestimate functional performance.• The study was unable to examine other contextual factors, such as the opportunity to learn or perform a skill, which may influence independence.For instance, adolescents may not be expected to run errands until they obtain a driver's license or learn to use public transportation.• The racial and ethnic distribution of the current sample was predominately non-Hispanic White and differed from that of nonresponders.This raises the possibility of selection bias, and findings should be interpreted with caution until replicated in more diverse samples. Research briefsEarly onset schizophrenia may have aberrant brain network compared to adult-onset schizophrenia

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Publication Details

Journal
The Brown University Child & Adolescent Psychopharmacology Update
Published
2026-08-27
DOI
https://doi.org/10.1002/cpu.31088
Primary Topic
Functional Brain Connectivity Studies
Type
article
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article

Early onset schizophrenia may have aberrant brain network compared to adult‐onset schizophrenia

Alison Knopf
The Brown University Child & Adolescent Psychopharmacology Update
Functional Brain Connectivity Studies
article

Early onset schizophrenia may have aberrant brain network compared to adult‐onset schizophrenia

Alison Knopf
article en

Abstract

are included in developmental monitoring resources from the US Centers for Disease Control and Prevention's Learn the Signs Act Early program and the American Academy of Pediatrics' Bright Futures guidelines."Because children with autism and other DD are likely to struggle with daily skills in adolescence, any way to identify them early to provide support to promote independence would be helpful, the researchers wrote."Future investigations are needed to explore whether services and supports to boost expressive language and fine motor skills and reduce attention problems in children with autism and other DD can improve acquisition of DLS and promote greater independence in adolescence." LimitationsThe researchers detailed the following limitations: • Reliance on a caregiver-reported measure of DLS, which may underestimate functional performance.• The study was unable to examine other contextual factors, such as the opportunity to learn or perform a skill, which may influence independence.For instance, adolescents may not be expected to run errands until they obtain a driver's license or learn to use public transportation.• The racial and ethnic distribution of the current sample was predominately non-Hispanic White and differed from that of nonresponders.This raises the possibility of selection bias, and findings should be interpreted with caution until replicated in more diverse samples. Research briefsEarly onset schizophrenia may have aberrant brain network compared to adult-onset schizophrenia

The Brown University Child & Adolescent Psychopharmacology UpdateVol. 28(9)
Openalex Percentile: Top 9%
Functional Brain Connectivity Studies
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Early onset schizophrenia may have aberrant brain network compared to adult‐onset schizophrenia — Alison Knopf · The Brown University Child & Adolescent Psychopharmacology Update (2026) | TGRS Research Map | TGRS