Green synthesis and investigation of biological activity of new pyrazole in ionic liquid
In this research we have synthesized new derivatives of pyrazoloazepine in high yields using multicomponent reaction of aniline, oxalyl chloride, iminoalkyl bromides, activated acetylenic compounds, and hydrazonoyl chlorides in ionic liquid at room temperature. Because of having NH group in the synthesized compounds, we investigate antioxidant property of some synthesized pyrazoloazepine by diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction experiment. Short time of reaction, high yields of product, easy separation of catalyst and products are some advantages of this procedure.
Authors
- IAU
Publication Details
- Journal
- Iranian Journal of Organic Chemistry (IranJOC) شیمی آلی ایران
- Published
- 2026-08-27
- DOI
- https://doi.org/10.82361/1251366
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.00