RCT shows ways to predict if SSRIs, CBT, or both are best for anxiety

Many youth with anxiety benefit from sertraline (SSRIs) or cognitive behavioral therapy (CBT), but response trajectories vary. So, researchers wanted to identify early markers of treatment response to either or both. Sequencing treatment strategies and identifying early nonresponse may improve outcomes. Instead of taking a “wait‐and‐see” approach as to what treatment works, there are ways to predict, according to the first randomized controlled trial (RCT) looking at how to predict response.

Authors

Publication Details

Journal
The Brown University Child & Adolescent Psychopharmacology Update
Published
2026-08-27
DOI
https://doi.org/10.1002/cpu.31084
Primary Topic
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Type
article
Field-Weighted Citation Impact
0.00
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article

RCT shows ways to predict if SSRIs, CBT, or both are best for anxiety

Alison Knopf
The Brown University Child & Adolescent Psychopharmacology Update
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
article

RCT shows ways to predict if SSRIs, CBT, or both are best for anxiety

Alison Knopf
article en

Abstract

Many youth with anxiety benefit from sertraline (SSRIs) or cognitive behavioral therapy (CBT), but response trajectories vary. So, researchers wanted to identify early markers of treatment response to either or both. Sequencing treatment strategies and identifying early nonresponse may improve outcomes. Instead of taking a “wait‐and‐see” approach as to what treatment works, there are ways to predict, according to the first randomized controlled trial (RCT) looking at how to predict response.

The Brown University Child & Adolescent Psychopharmacology UpdateVol. 28(9)
Good health and well-being
Openalex Percentile: Top 6%
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
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