Reconceptualizing Cerebral Palsy as a Lifelong Condition Characterized by Systemic and Accelerated Biological Decline

Cerebral palsy (CP), the most common childhood-onset disability worldwide, affects an estimated 50 million individuals globally. Although most individuals with CP are adults, CP education and training remain heavily concentrated within pediatric subspecialties, contributing to substantial gaps in adult care. At the same time, emerging evidence demonstrates that CP is associated with progressive multisystem, metabolic, musculoskeletal, and cellular changes across the lifespan, despite the original brain injury being nonprogressive. Current educational models, however, continue to frame CP primarily as a pediatric motor disorder, limiting clinician preparedness to address the complex health needs of aging adults with CP. This perspective paper argues that physiatry is uniquely positioned to lead a paradigm shift in residency education by reframing CP as a lifelong condition characterized by systemic involvement and accelerated biological aging. We propose a lifespan-oriented educational framework that integrates contemporary understanding of CP pathophysiology, multimorbidity, functional decline, and rehabilitation needs across adulthood. Expanding CP-focused education within physiatry residency training may improve clinician preparedness and represents one component of broader efforts to improve healthcare access, interdisciplinary care coordination, and long-term outcomes for adolescents and adults aging with CP.

Authors

Institutions

Publication Details

Journal
American Journal of Physical Medicine & Rehabilitation
Published
2026-08-27
DOI
https://doi.org/10.1097/phm.0000000000003144
Primary Topic
Cerebral Palsy and Movement Disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Reconceptualizing Cerebral Palsy as a Lifelong Condition Characterized by Systemic and Accelerated Biological Decline

Joline E. Brandenburg, Shannon Strader, Andrea A. Domenighetti
American Journal of Physical Medicine & Rehabilitation
Cerebral Palsy and Movement Disorders
article

Reconceptualizing Cerebral Palsy as a Lifelong Condition Characterized by Systemic and Accelerated Biological Decline

Joline E. Brandenburg, Shannon Strader, Andrea A. Domenighetti
article en

Abstract

Cerebral palsy (CP), the most common childhood-onset disability worldwide, affects an estimated 50 million individuals globally. Although most individuals with CP are adults, CP education and training remain heavily concentrated within pediatric subspecialties, contributing to substantial gaps in adult care. At the same time, emerging evidence demonstrates that CP is associated with progressive multisystem, metabolic, musculoskeletal, and cellular changes across the lifespan, despite the original brain injury being nonprogressive. Current educational models, however, continue to frame CP primarily as a pediatric motor disorder, limiting clinician preparedness to address the complex health needs of aging adults with CP. This perspective paper argues that physiatry is uniquely positioned to lead a paradigm shift in residency education by reframing CP as a lifelong condition characterized by systemic involvement and accelerated biological aging. We propose a lifespan-oriented educational framework that integrates contemporary understanding of CP pathophysiology, multimorbidity, functional decline, and rehabilitation needs across adulthood. Expanding CP-focused education within physiatry residency training may improve clinician preparedness and represents one component of broader efforts to improve healthcare access, interdisciplinary care coordination, and long-term outcomes for adolescents and adults aging with CP.

American Journal of Physical Medicine & Rehabilitation
Northwestern University (US), Shirley Ryan AbilityLab (US), Northwestern University (PH), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US), Northwestern Medicine (US)
Quality Education
Openalex Percentile: Top 10%
Cerebral Palsy and Movement Disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.