An Expert Perspective on a New Recombinant Pertussis-Only Vaccine and Its Potential Clinical and Programmatic Advantages in Australia, New Zealand, and Beyond

Despite high childhood coverage and booster doses of pertussis vaccination across the life course, pertussis (whooping cough) outbreaks continue to occur, including in Australia and New Zealand. In January 2026, the European Medicines Agency (EMA) granted marketing authorisation to a new pertussis-only booster vaccine (VacPertagenTM): the first time in two decades that a new acellular pertussis vaccine has been approved in the European Union. Anticipating future licensure of the vaccine in Australia and New Zealand, an expert panel was convened to discuss the clinical and programmatic advantages that this new vaccine may offer in the context of current pertussis epidemiology and vaccination strategies inSuch advantages may also be applicable to other high-income countries experiencing ongoing pertussis outbreaks.

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Publication Details

Journal
Vaccines
Published
2026-08-26
DOI
https://doi.org/10.3390/vaccines14090736
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00

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article

An Expert Perspective on a New Recombinant Pertussis-Only Vaccine and Its Potential Clinical and Programmatic Advantages in Australia, New Zealand, and Beyond

Mary Nowlan, Rodney Pearce, Anita H.J. van den Biggelaar, Peter Richmond et al.
Vaccines
Bacterial Infections and Vaccines
article

An Expert Perspective on a New Recombinant Pertussis-Only Vaccine and Its Potential Clinical and Programmatic Advantages in Australia, New Zealand, and Beyond

Mary Nowlan, Rodney Pearce, Anita H.J. van den Biggelaar, Peter Richmond, Terry Nolan, Frank Beard, Peter McIntyre, Catherine Hughes, Annette K. Regan
article en

Abstract

Despite high childhood coverage and booster doses of pertussis vaccination across the life course, pertussis (whooping cough) outbreaks continue to occur, including in Australia and New Zealand. In January 2026, the European Medicines Agency (EMA) granted marketing authorisation to a new pertussis-only booster vaccine (VacPertagenTM): the first time in two decades that a new acellular pertussis vaccine has been approved in the European Union. Anticipating future licensure of the vaccine in Australia and New Zealand, an expert panel was convened to discuss the clinical and programmatic advantages that this new vaccine may offer in the context of current pertussis epidemiology and vaccination strategies inSuch advantages may also be applicable to other high-income countries experiencing ongoing pertussis outbreaks.

VaccinesVol. 14(9)
South Australia Pathology (AU), The University of Sydney (AU), University of Auckland (NZ), University of California, Los Angeles (US), The Kids Research Institute Australia (AU), The University of Western Australia (AU), National Heart Foundation of Australia (AU), Dunedin Public Hospital (NZ), Peter Doherty Institute (AU), Sydney Local Health District (AU), Western Sydney University (AU), University of Otago (NZ)
BioNet-Asia
Openalex Percentile: Top 13%
Bacterial Infections and Vaccines
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