High Frequency of Circulating IL-4R + SELL + Naïve B Cells Is Associated with Functional Cure in Chronic Hepatitis B Patients Receiving Antiviral Treatment
Although hepatitis B surface antigen (HBsAg)-specific B cells have been partially characterized in chronic hepatitis B (CHB), the role of Naïve B cells and their potential relevance to functional cure remain insufficiently explored. Here, we aimed to characterize the naïve B-cell subsets between cured and uncured patients with CHB.
Authors
- Jun‐Liang Fu (ORCID: https://orcid.org/0000-0003-1712-4256)
- Cheng Zhen (ORCID: https://orcid.org/0000-0003-2396-1261)
- Chao Zhang (ORCID: https://orcid.org/0000-0001-8126-8145)
- Fu‐Sheng Wang (ORCID: https://orcid.org/0000-0002-8043-6685)
- Huan Wang (ORCID: https://orcid.org/0000-0002-1403-5314)
- Yangliu Chen
- Chunmei Bao
- Ruonan Xu
- Jing Li
- Lili Tang
- Yue Yuan
- Honghong Liu
- Lin Cao
- Tao Yang
- Jinwen Song
- Yanmei Jiao
- Yang Zhang
- Yingying Gao
- Jinhong Yuan
Institutions
- Peking University (CN)
- Chinese PLA General Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-08-26
- DOI
- https://doi.org/10.14218/jcth.2026.00356
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00