Reporting Completeness of Biliary Atresia Organoid Studies: A Scoping Review and Structured Audit
Biliary atresia (BA) is the leading cause of pediatric obstructive cholestasis and a major indication for liver transplantation in infants. Organoid models are increasingly used to investigate BA pathogenesis and therapeutic responses, but incomplete methodological and clinical reporting may limit cross-study comparison and translational interpretation. This study aimed to map the landscape of BA-related organoid research, identify major reporting gaps, and propose Biliary Atresia Minimum Reporting Standard (BA-MRS) as a preliminary framework for improving reporting completeness.
Authors
- Jinshi Huang (ORCID: https://orcid.org/0000-0003-2857-632X)
- Guantong Li
- Yanan Zhang
- Junmin Liao
- Yong Zhao
- Yichao Gu
- Kaiyun Hua
- Dayan Sun
- Dingding Wang
- Shuangshuang Li
Institutions
- Beijing Children’s Hospital (CN)
- Jiangxi Provincial Children's Hospital (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-08-26
- DOI
- https://doi.org/10.14218/jcth.2026.00352
- Primary Topic
- Pediatric Hepatobiliary Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00