Reporting Completeness of Biliary Atresia Organoid Studies: A Scoping Review and Structured Audit

Biliary atresia (BA) is the leading cause of pediatric obstructive cholestasis and a major indication for liver transplantation in infants. Organoid models are increasingly used to investigate BA pathogenesis and therapeutic responses, but incomplete methodological and clinical reporting may limit cross-study comparison and translational interpretation. This study aimed to map the landscape of BA-related organoid research, identify major reporting gaps, and propose Biliary Atresia Minimum Reporting Standard (BA-MRS) as a preliminary framework for improving reporting completeness.

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Publication Details

Journal
Journal of Clinical and Translational Hepatology
Published
2026-08-26
DOI
https://doi.org/10.14218/jcth.2026.00352
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Reporting Completeness of Biliary Atresia Organoid Studies: A Scoping Review and Structured Audit

Jinshi Huang, Guantong Li, Yanan Zhang, Junmin Liao et al.
Journal of Clinical and Translational Hepatology
Pediatric Hepatobiliary Diseases and Treatments
article

Reporting Completeness of Biliary Atresia Organoid Studies: A Scoping Review and Structured Audit

Jinshi Huang, Guantong Li, Yanan Zhang, Junmin Liao, Yong Zhao, Yichao Gu, Kaiyun Hua, Dayan Sun, Dingding Wang, Shuangshuang Li
article en

Abstract

Biliary atresia (BA) is the leading cause of pediatric obstructive cholestasis and a major indication for liver transplantation in infants. Organoid models are increasingly used to investigate BA pathogenesis and therapeutic responses, but incomplete methodological and clinical reporting may limit cross-study comparison and translational interpretation. This study aimed to map the landscape of BA-related organoid research, identify major reporting gaps, and propose Biliary Atresia Minimum Reporting Standard (BA-MRS) as a preliminary framework for improving reporting completeness.

Journal of Clinical and Translational HepatologyVol. 000(000)
Beijing Children’s Hospital (CN), Jiangxi Provincial Children's Hospital (CN)
Openalex Percentile: Top 8%
Pediatric Hepatobiliary Diseases and Treatments
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