Mortality of Individuals With PRNP Variants Associated With Prion Disease in the United States, 1998–2024
To characterize the survival of individuals with pathogenic PRNP variants—including to estimate annual hazards, to judge the accuracy of previously reported survival data, and to evaluate the utility of public record searches in determining vital status.
Authors
- Katie Glisic
- Eric Vallabh Minikel (ORCID: https://orcid.org/0000-0003-2206-1608)
- Sonia M. Vallabh (ORCID: https://orcid.org/0000-0003-3824-2702)
- Brian S. Appleby (ORCID: https://orcid.org/0000-0003-2275-3292)
- Daniel A. Sprague (ORCID: https://orcid.org/0009-0003-1355-0298)
- Keisi Kotobelli
- Yuan Lian
Institutions
- Broad Institute (US)
- Prion Alliance (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Neurology Genetics
- Published
- 2026-08-26
- DOI
- https://doi.org/10.1212/nxg.0000000000200423
- Primary Topic
- Prion Diseases and Protein Misfolding
- Type
- article
- Field-Weighted Citation Impact
- 0.00