An Assessment of Reliability Estimation Methods for Binomial Health Care Quality Measures

We evaluated the performance of commonly used methods for estimating the reliability of binomial health care quality measures using simulated datasets spanning a range of performance score means and variances, numbers of entities, and patient sample sizes. For each simulation, reliability was estimated for all selected methods and compared with the known true reliability derived from the simulation parameters, with methods assessed on their accuracy and precision. Logistic regression with reliability estimated on the outcome scale demonstrated the highest accuracy and precision among all methods evaluated. The widely used Adams beta-binomial method performed poorly, although a modification recommended by Nieser and Harris substantially improved its performance. These approaches are applicable only to binomial measures. Among methods that can be applied to both binomial and continuous measures, permutation resampling of the Spearman rank correlation coefficient was the most accurate and precise, outperforming other commonly used approaches. Overall, for binomial quality measures, logistic regression on the outcome scale is the preferred method for reliability estimation, followed closely by the modified beta-binomial approach, while for non-binomial measures, permutation-based Spearman rank correlation appears to be the most suitable method.

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Publication Details

Journal
Statistics in Medicine
Published
2026-08-25
DOI
https://doi.org/10.1002/sim.70729
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
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article

An Assessment of Reliability Estimation Methods for Binomial Health Care Quality Measures

Jeffrey Geppert, Po‐Hsu Chen, Laura Aume, William White
Statistics in Medicine
Sepsis Diagnosis and Treatment
article

An Assessment of Reliability Estimation Methods for Binomial Health Care Quality Measures

Jeffrey Geppert, Po‐Hsu Chen, Laura Aume, William White
article en

Abstract

We evaluated the performance of commonly used methods for estimating the reliability of binomial health care quality measures using simulated datasets spanning a range of performance score means and variances, numbers of entities, and patient sample sizes. For each simulation, reliability was estimated for all selected methods and compared with the known true reliability derived from the simulation parameters, with methods assessed on their accuracy and precision. Logistic regression with reliability estimated on the outcome scale demonstrated the highest accuracy and precision among all methods evaluated. The widely used Adams beta-binomial method performed poorly, although a modification recommended by Nieser and Harris substantially improved its performance. These approaches are applicable only to binomial measures. Among methods that can be applied to both binomial and continuous measures, permutation resampling of the Spearman rank correlation coefficient was the most accurate and precise, outperforming other commonly used approaches. Overall, for binomial quality measures, logistic regression on the outcome scale is the preferred method for reliability estimation, followed closely by the modified beta-binomial approach, while for non-binomial measures, permutation-based Spearman rank correlation appears to be the most suitable method.

Statistics in MedicineVol. 45(20-22)
Battelle (US)
Openalex Percentile: Top 10%
Sepsis Diagnosis and Treatment
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An Assessment of Reliability Estimation Methods for Binomial Health Care Quality Measures — Jeffrey Geppert, Po‐Hsu Chen, et al. · Statistics in Medicine (2026) | TGRS Research Map | TGRS