Lung Ultrasound-Guided Non-Fiberobronchoscopic Bronchoalveolar Lavage for Neonatal Atelectatic Pulmonary Disease Treatment: Clinical Practice Guidelines Based on International Expert Consensus

Severe pulmonary diseases, including atelectasis, pneumonia, and meconium aspiration syndrome, are major causes of neonatal respiratory distress, weaning difficulties, ventilator or oxygen dependence, prolonged oxygen requirements, extended hospitalization, and poor prognosis. The lack of simple and effective treatment strategies seriously endangers the survival and health of newborns, particularly premature infants. Recent advances in lung ultrasound (LUS) technology have made LUS-guided non-fiberobronchoscopic bronchoalveolar lavage (NFB-BAL) a promising solution. This approach addresses the limitations of conventional BAL in neonates by enabling accurate diagnosis, precise lesion localization, and dynamic procedural monitoring, hence reducing complications. Based on international expert consensus, these guidelines were developed to improve knowledge and promote the application of this technology and enhance operational standardization to ensure its effectiveness and safety. These guidelines contain 17 recommendations on 13 key clinical issues for reference and implementation in clinical practice. The wide application of these guidelines is expected to help significantly improve the prognosis of critically ill newborns with atelectatic pulmonary diseases.

Authors

Institutions

Publication Details

Journal
Diagnostics
Published
2026-08-25
DOI
https://doi.org/10.3390/diagnostics16172712
Primary Topic
Ultrasound in Clinical Applications
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Lung Ultrasound-Guided Non-Fiberobronchoscopic Bronchoalveolar Lavage for Neonatal Atelectatic Pulmonary Disease Treatment: Clinical Practice Guidelines Based on International Expert Consensus

Chuming You, Mengru Zhao, Erich Sorantin, Xiao-Ling Ren et al.
Diagnostics
Ultrasound in Clinical Applications
article

Lung Ultrasound-Guided Non-Fiberobronchoscopic Bronchoalveolar Lavage for Neonatal Atelectatic Pulmonary Disease Treatment: Clinical Practice Guidelines Based on International Expert Consensus

Chuming You, Mengru Zhao, Erich Sorantin, Xiao-Ling Ren, Jovan Lovrenski, Yogen Singh, Kai‐Sheng Hsieh, Abhay Lodha, Cai-Xuan Xie, Hong Yuan, Piotr Kruczek, Jing Liu, Dalibor Kurepa, Stefano Nobile, Zun-Jie Liu, Lingyun Bao, Yi-na Ye, Xiaoxia Li, Xiaoxiao Wang, Lu Liu, Lili Zang, Yali Guo, Peng Jiang, Zhen-Yu Liang, Shuo Li, Jia-Gen Cen, Xian Zhang, Tsu F. Yeh, Zai-Li Feng, Ning Li, Wen-Ping Wang, Ayinuer Maimaitili, Giovanni Volpicelli, Wei Fu, Qiong Meng, Bi-Ying Deng, Rui-Yan Shan, Ying-Jun Wang, Pradeep Suryawanshi
article en

Abstract

Severe pulmonary diseases, including atelectasis, pneumonia, and meconium aspiration syndrome, are major causes of neonatal respiratory distress, weaning difficulties, ventilator or oxygen dependence, prolonged oxygen requirements, extended hospitalization, and poor prognosis. The lack of simple and effective treatment strategies seriously endangers the survival and health of newborns, particularly premature infants. Recent advances in lung ultrasound (LUS) technology have made LUS-guided non-fiberobronchoscopic bronchoalveolar lavage (NFB-BAL) a promising solution. This approach addresses the limitations of conventional BAL in neonates by enabling accurate diagnosis, precise lesion localization, and dynamic procedural monitoring, hence reducing complications. Based on international expert consensus, these guidelines were developed to improve knowledge and promote the application of this technology and enhance operational standardization to ensure its effectiveness and safety. These guidelines contain 17 recommendations on 13 key clinical issues for reference and implementation in clinical practice. The wide application of these guidelines is expected to help significantly improve the prognosis of critically ill newborns with atelectatic pulmonary diseases.

DiagnosticsVol. 16(17)
Cincinnati Children's Hospital Medical Center (US), Royal College of Physicians of Edinburgh (GB), Jinan University (CN), University of Novi Sad (RS), Guangdong Medical College (CN), China Medical University (TW), Medical University of Graz (AT), Kunming Medical University (CN), John H. Stroger, Jr. Hospital of Cook County (US), Beijing Chao-Yang Hospital, Capital Medical University (CN), Agostino Gemelli University Polyclinic (IT), Yuhuangding Hospital (CN), Magna Graecia University (IT), Third Affiliated Hospital of Southern Medical University (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Kunming Children's Hospital (CN), Zhoukou Normal University (CN), Cuiavian University (PL), Yili Friendship Hospital (CN), Dongguan People’s Hospital (CN), China Medical University Hospital (TW), Zhoukou City Academy of Agricultural Sciences (CN), The People's Hospital of LinXia (CN), Guangdong Provincial People's Hospital (CN), Liaocheng People's Hospital (CN), UC Davis Children's Hospital (US), Beijing Obstetrics and Gynecology Hospital (CN), Southern Medical University (CN), Bharati Vidyapeeth (Deemed to be University) (IN), Guangzhou Medical University (CN)
Openalex Percentile: Top 9%
Ultrasound in Clinical Applications
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.