Rectal Gastrointestinal Stromal Tumor Poor Response to Imatinib: A Case Report

A 63-year-old man presented with persistent constipation lasting 6.5 months. Digital rectal examination revealed a soft-tissue lesion near the anal verge without bleeding. Further evaluation identified a rectal mass. Treatment with imatinib for 6 months showed no significant response. The patient subsequently underwent surgical resection, with favorable short-term clinical outcomes.

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Publication Details

Journal
Clinical Case Reports
Published
2026-08-25
DOI
https://doi.org/10.1002/ccr3.73395
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
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article

Rectal Gastrointestinal Stromal Tumor Poor Response to Imatinib: A Case Report

Tooraj Zandbaf, Majid Einakchi, Alireza Samimi, Narges Mesbah
Clinical Case Reports
Gastrointestinal Tumor Research and Treatment
article

Rectal Gastrointestinal Stromal Tumor Poor Response to Imatinib: A Case Report

Tooraj Zandbaf, Majid Einakchi, Alireza Samimi, Narges Mesbah
article en

Abstract

A 63-year-old man presented with persistent constipation lasting 6.5 months. Digital rectal examination revealed a soft-tissue lesion near the anal verge without bleeding. Further evaluation identified a rectal mass. Treatment with imatinib for 6 months showed no significant response. The patient subsequently underwent surgical resection, with favorable short-term clinical outcomes.

Clinical Case ReportsVol. 14(9)
Mashhad University of Medical Sciences (IR), Islamic Azad University, Mashhad (IR)
No poverty
Openalex Percentile: Top 9%
Gastrointestinal Tumor Research and Treatment
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Rectal Gastrointestinal Stromal Tumor Poor Response to Imatinib: A Case Report — Tooraj Zandbaf, Majid Einakchi, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS