Turkish validity and reliability of the Migraine Treatment Optimization Questionnaire-4 (MTOQ-4)

The Migraine Treatment Optimization Questionnaire-4 (MTOQ-4) is a brief patient-reported instrument developed to evaluate the effectiveness of acute migraine treatment. This study aimed to assess the validity and reliability of the Turkish version of MTOQ-4. This methodological study was conducted between May and November 2025. After obtaining permission from the scale developer, the translation and cultural adaptation process included forward translation, expert panel review, back translation, and pilot testing. The study population consisted of adults diagnosed with migraine who attended a family medicine outpatient clinic. Sociodemographic data and the MTOQ-4 were administered face-to-face. Internal consistency was assessed using Cronbach’s alpha. Construct validity was evaluated using exploratory factor analysis. Kaiser-Mayer-Olkin(KMO) and Bartlett’s tests were applied to assess sample adequacy. Statistical analyses were performed using SPSS 23 and AMOS. The mean content validity index (S-CVI/Ave) at the scale level was calculated as 0.95. The Cronbach's Alpha coefficient, calculated to determine the internal consistency of the MTOQ-4 scale, was found to be 0.829. The KMO value was determined as 0.7887, and the Bartlett test was statistically significant ( p < 0.001). The exploratory factor analysis showed that all factor loadings were above 0.60. The Turkish version of MTOQ-4 is expected to be a valid and reliable instrument for evaluating acute migraine treatment effectiveness in primary care.