Conceptualising heart disease prediction through a unified framework combining clinical theory and machine learning models

A hybrid framework for a comprehensive evaluation of machine learning and transformer-based models for cardiovascular risk prediction by integrating structured clinical data with unstructured clinical narratives is included in this study. The structured data includes demographic and diagnostic variables like patient information and test results, while unstructured data is derived from electronic health records such as clinical notes. Through preprocessing, feature engineering, and semantic embedding using transformer-based models, the system leverages the complementary strengths of both data types. By analysing and processing this unstructured information, this project aims to improve the predictions for heart disease. The results show that it is feasible to make better predictions and gain valuable insights by merging these two types of data. Such analysis is essential because structured data alone often overlooks fine-grained clinical indicators found in narrative texts. Integrating unstructured data allows for a more holistic view of patient health, leading to earlier detection, personalized interventions, and improved decision-making in clinical settings.

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Publication Details

Journal
Discover Artificial Intelligence
Published
2026-08-25
DOI
https://doi.org/10.1007/s44163-026-02010-8
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
0.00
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article

Conceptualising heart disease prediction through a unified framework combining clinical theory and machine learning models

Diana Olivia, Vibha Prabhu, Yarakam Shiva Chaitanya Reddy, Ajay Kumar Yeldi
Discover Artificial Intelligence
Machine Learning in Healthcare
article

Conceptualising heart disease prediction through a unified framework combining clinical theory and machine learning models

Diana Olivia, Vibha Prabhu, Yarakam Shiva Chaitanya Reddy, Ajay Kumar Yeldi
article en

Abstract

A hybrid framework for a comprehensive evaluation of machine learning and transformer-based models for cardiovascular risk prediction by integrating structured clinical data with unstructured clinical narratives is included in this study. The structured data includes demographic and diagnostic variables like patient information and test results, while unstructured data is derived from electronic health records such as clinical notes. Through preprocessing, feature engineering, and semantic embedding using transformer-based models, the system leverages the complementary strengths of both data types. By analysing and processing this unstructured information, this project aims to improve the predictions for heart disease. The results show that it is feasible to make better predictions and gain valuable insights by merging these two types of data. Such analysis is essential because structured data alone often overlooks fine-grained clinical indicators found in narrative texts. Integrating unstructured data allows for a more holistic view of patient health, leading to earlier detection, personalized interventions, and improved decision-making in clinical settings.

Discover Artificial IntelligenceVol. 6(1)
Manipal Academy of Higher Education (IN)
Peace, Justice and strong institutions
Openalex Percentile: Top 8%
Machine Learning in Healthcare
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Conceptualising heart disease prediction through a unified framework combining clinical theory and machine learning models — Diana Olivia, Vibha Prabhu, et al. · Discover Artificial Intelligence (2026) | TGRS Research Map | TGRS