Temperament as a Risk Factor for Clinical Diagnosis During the Transition From Childhood Through Adolescence and Young Adulthood: A 16-Year Multimethod Longitudinal Study
Identifying early temperamental predictors of later psychopathology is crucial for detecting at-risk individuals and implementing targeted prevention efforts. However, there is limited research using laboratory-based observations of temperament and “gold-standard” assessments of psychiatric disorders across early adolescence and young adulthood. Using a multimethod, prospective longitudinal study ( N = 291), we investigated whether temperament (i.e., behavioral inhibition [BI], exuberance) observed at 24 and 36 months predicted the likelihood of psychiatric disorders across adolescence/young adulthood. Results suggested that early childhood BI was not predictive of anxiety diagnosis over time; however, exuberance predicted attention-deficit/hyperactivity disorder at ages 12, 15, and 18 years. Results add to prior work that has rarely found direct relations between early temperament and psychopathology and highlight early adolescence/young adulthood as a vulnerable time for the development of psychopathology.
Authors
- Nicole E. Lorenzo (ORCID: https://orcid.org/0000-0002-0799-3119)
- Selin Zeytinoglu (ORCID: https://orcid.org/0000-0002-2736-4061)
- Hong N.T. Bui (ORCID: https://orcid.org/0000-0002-8782-0129)
- Nathan A. Fox (ORCID: https://orcid.org/0000-0003-4452-4503)
- Daniel S. Pine
- Heather Henderson
- Andrea Chronis-Tuscano
- Kathyrn A. Degnan
Institutions
- National Institutes of Health (US)
- University of Waterloo (CA)
- American University (US)
- University of Maryland, College Park (US)
- Catholic University of America (US)
Publication Details
- Journal
- Clinical Psychological Science
- Published
- 2026-08-25
- DOI
- https://doi.org/10.1177/21677026251315150
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Mental Health