Non-Pharmacological Management of Charcot–Marie–Tooth Disease: A Case Report

Charcot–Marie–Tooth (CMT) is a rare, genetic, slowly progressive disorder that affects nerve conduction, particularly in the limbs and, therefore, the muscles. Phenotypes vary, but the impact on quality of life is always present. CMT1A is the most prevalent type. There is no pharmacological cure, so physiotherapy is essential, but nutritional and exercise aspects are rarely considered. In this case report, we demonstrate how, even in this condition, effective results can be achieved with strength training if properly supervised, coordinated with physiotherapy, and combined with an appropriate nutritional plan.

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Publication Details

Journal
Muscles
Published
2026-08-25
DOI
https://doi.org/10.3390/muscles5030059
Primary Topic
Hereditary Neurological Disorders
Type
article
Field-Weighted Citation Impact
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article

Non-Pharmacological Management of Charcot–Marie–Tooth Disease: A Case Report

Erika Cione, Roberto Cannataro, Irene Carantini, Francesco Ferraro
Muscles
Hereditary Neurological Disorders
article

Non-Pharmacological Management of Charcot–Marie–Tooth Disease: A Case Report

Erika Cione, Roberto Cannataro, Irene Carantini, Francesco Ferraro
article en

Abstract

Charcot–Marie–Tooth (CMT) is a rare, genetic, slowly progressive disorder that affects nerve conduction, particularly in the limbs and, therefore, the muscles. Phenotypes vary, but the impact on quality of life is always present. CMT1A is the most prevalent type. There is no pharmacological cure, so physiotherapy is essential, but nutritional and exercise aspects are rarely considered. In this case report, we demonstrate how, even in this condition, effective results can be achieved with strength training if properly supervised, coordinated with physiotherapy, and combined with an appropriate nutritional plan.

MusclesVol. 5(3)
Dynamic Systems (United States) (US), Charcot-Marie-Tooth Association (US), Azienda Ospedaliera Carlo Poma (IT), University of Calabria (IT)
Zero hunger
Openalex Percentile: Top 16%
Hereditary Neurological Disorders
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