Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

The patient, a 77-year-old male smoker, presented to the Emergency Department with dyspnea, cough, fever, night sweats, and 12 kg weight loss, initially suggesting COPD or lung cancer. Chest CT revealed a right upper lobe mass, pleural effusion, and lymphadenopathy, prompting suspicion of malignancy. Bronchoalveolar lavage was negative for acid-fast bacilli (AFB), and abdominal/pelvic CT showed no metastases. Transthoracic biopsy confirmed pulmonary TB with caseating granulomas and AFB, with no evidence of malignancy. A 6-month anti-TB regimen resolved all symptoms and lesions.

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Publication Details

Journal
Clinical Case Reports
Published
2026-08-25
DOI
https://doi.org/10.1002/ccr3.73278
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
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article

Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

Sara Samadi, Mahnaz Mozdourian, Pejman Hosseinzadeh, Sayed Mortaza Fayez et al.
Clinical Case Reports
Diagnosis and treatment of tuberculosis
article

Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

Sara Samadi, Mahnaz Mozdourian, Pejman Hosseinzadeh, Sayed Mortaza Fayez, Shirin Taraz Jamshidi
article en

Abstract

The patient, a 77-year-old male smoker, presented to the Emergency Department with dyspnea, cough, fever, night sweats, and 12 kg weight loss, initially suggesting COPD or lung cancer. Chest CT revealed a right upper lobe mass, pleural effusion, and lymphadenopathy, prompting suspicion of malignancy. Bronchoalveolar lavage was negative for acid-fast bacilli (AFB), and abdominal/pelvic CT showed no metastases. Transthoracic biopsy confirmed pulmonary TB with caseating granulomas and AFB, with no evidence of malignancy. A 6-month anti-TB regimen resolved all symptoms and lesions.

Clinical Case ReportsVol. 14(9)
Mashhad University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 8%
Diagnosis and treatment of tuberculosis
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