Macular serpiginous chorioretinitis associated with Francisella tularensis: A case report

PURPOSE: To report a rare case of bilateral macular serpiginous chorioretinitis associated with Francisella tularensis infection following rabbit exposure. METHODS: Observational case report with multimodal retinal imaging and extensive systemic and serologic evaluation. RESULTS: The patient presented with rapidly progressive bilateral central visual loss and placoid macular lesions. Serologic testing confirmed Francisella tularensis infection. Treatment with doxycycline led to regression of inflammatory changes, with residual outer retinal atrophy. CONCLUSION: This case highlights tularemia as a rare infectious trigger of macular serpiginous chorioretinitis and underscores the importance of considering zoonotic infections in atypical or rapidly progressive chorioretinal inflammatory disease.

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Publication Details

Journal
Retinal Cases & Brief Reports
Published
2026-08-25
DOI
https://doi.org/10.1097/icb.0000000000001977
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
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article

Macular serpiginous chorioretinitis associated with Francisella tularensis: A case report

Jeanne Martine Gunzinger, Simona Simmen, Mayss Al‐Sheikh, Eva Manuela Friedl et al.
Retinal Cases & Brief Reports
Bacillus and Francisella bacterial research
article

Macular serpiginous chorioretinitis associated with Francisella tularensis: A case report

Jeanne Martine Gunzinger, Simona Simmen, Mayss Al‐Sheikh, Eva Manuela Friedl, Daniel Barthelmes, Barbara Hasse, Stefan Langenegger, Sandrine Zweifel
article en

Abstract

PURPOSE: To report a rare case of bilateral macular serpiginous chorioretinitis associated with Francisella tularensis infection following rabbit exposure. METHODS: Observational case report with multimodal retinal imaging and extensive systemic and serologic evaluation. RESULTS: The patient presented with rapidly progressive bilateral central visual loss and placoid macular lesions. Serologic testing confirmed Francisella tularensis infection. Treatment with doxycycline led to regression of inflammatory changes, with residual outer retinal atrophy. CONCLUSION: This case highlights tularemia as a rare infectious trigger of macular serpiginous chorioretinitis and underscores the importance of considering zoonotic infections in atypical or rapidly progressive chorioretinal inflammatory disease.

Retinal Cases & Brief Reports
University Hospital of Zurich (CH), Sight and Life (CH)
Good health and well-being
Openalex Percentile: Top 17%
Bacillus and Francisella bacterial research
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Macular serpiginous chorioretinitis associated with Francisella tularensis: A case report — Jeanne Martine Gunzinger, Simona Simmen, et al. · Retinal Cases & Brief Reports (2026) | TGRS Research Map | TGRS