Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells

{"Organelle":[0],"movements":[1,89,135,157],"in":[2,47,71,133,165],"plants":[3],"are":[4],"driven":[5],"by":[6,120],"myosin":[7],"XI":[8],"motors":[9],"moving":[10],"along":[11],"the":[12,41,55,91,113,156],"actin":[13,126],"filament":[14],"cytoskeleton.":[15],"Several":[16],"experiments":[17],"suggested":[18],"that":[19,162],"indirect":[20],"effects":[21,56,103],"such":[22],"as":[23],"organelle-organelle":[24],"interactions":[25],"or":[26],"hydrodynamic":[27],"flow":[28],"may":[29],"be":[30],"responsible":[31],"for":[32],"organelle":[33,163],"movements.":[34],"To":[35],"test":[36],"these":[37,58,147],"models,":[38],"we":[39],"altered":[40],"motile":[42],"behavior":[43],"of":[44,57,74,90,104,115,125,137,158,178],"specific":[45,144,159],"organelles":[46,66,79,160],"Nicotiana":[48],"benthamiana":[49],"leaf":[50],"epidermal":[51],"cells":[52,167],"and":[53,95,140],"examined":[54],"perturbations":[59],"on":[60,107],"other":[61],"organelles.":[62,109,148,179],"Recruiting":[63],"myosins":[64],"to":[65,80,87,122,154],"with":[67,83],"\\"Booster\\"":[68],"constructs":[69,85,106],"resulted":[70,132],"significant":[72],"increases":[73],"linear":[75],"motions,":[76],"while":[77],"binding":[78],"cortical":[81],"microtubules":[82],"\\"Anchor\\"":[84],"lead":[86],"diminished":[88],"targeted":[92],"mitochondria,":[93],"peroxisomes":[94],"ER,":[96],"respectively.":[97],"We":[98],"did":[99],"not":[100],"observe":[101],"consistent":[102],"Anchor":[105],"non-targeted":[108],"Mitochondrial":[110],"Boosters":[111,131],"increased":[112],"motility":[114,164],"all":[116],"tested":[117],"organelles,":[118],"presumably":[119],"leading":[121],"a":[123,143],"reorganization":[124],"filaments.":[127],"By":[128],"contrast,":[129],"ER":[130],"enhanced":[134],"only":[136],"Golgi":[138],"stacks":[139],"peroxisomes,":[141],"suggesting":[142],"interaction":[145],"between":[146,175],"Collectively,":[149],"this":[150],"novel":[151],"engineering":[152],"approach":[153],"modify":[155],"demonstrates":[161],"plant":[166],"can":[168],"occur":[169],"independently":[170],"but":[171],"nevertheless":[172],"is":[173],"coordinated":[174],"different":[176],"types":[177]}

Authors

Institutions

Publication Details

Journal
Journal of Cell Science
Published
2026-08-24
DOI
https://doi.org/10.1242/jcs.264573
Primary Topic
Microtubule and mitosis dynamics
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells

Andreas Nebenführ, Alex Keith, Kylie Smith, Jin-Mo Gu
Journal of Cell Science
Microtubule and mitosis dynamics
article

Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells

Andreas Nebenführ, Alex Keith, Kylie Smith, Jin-Mo Gu
article en

Abstract

Organelle movements in plants are driven by myosin XI motors moving along the actin filament cytoskeleton. Several experiments suggested that indirect effects such as organelle-organelle interactions or hydrodynamic flow may be responsible for organelle movements. To test these models, we altered the motile behavior of specific organelles in Nicotiana benthamiana leaf epidermal cells and examined the effects of these perturbations on other organelles. Recruiting myosins to organelles with "Booster" constructs resulted in significant increases of linear motions, while binding organelles to cortical microtubules with "Anchor" constructs lead to diminished movements of the targeted mitochondria, peroxisomes and ER, respectively. We did not observe consistent effects of Anchor constructs on non-targeted organelles. Mitochondrial Boosters increased the motility of all tested organelles, presumably by leading to a reorganization of actin filaments. By contrast, ER Boosters resulted in enhanced movements only of Golgi stacks and peroxisomes, suggesting a specific interaction between these organelles. Collectively, this novel engineering approach to modify the movements of specific organelles demonstrates that organelle motility in plant cells can occur independently but nevertheless is coordinated between different types of organelles.

Journal of Cell Science
University of Tennessee at Knoxville (US)
Openalex Percentile: Top 13%
Microtubule and mitosis dynamics
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.