Expert consensus on the application of nonsteroidal anti-inflammatory drugs for perioperative analgesia

Although nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in multimodal pain management under the concept of enhanced recovery after surgery (ERAS), adverse reactions and safety events caused by their unreasonable use have become increasingly prominent. Drawing on the latest literature and evidence-based medicine domestically and abroad, and based on the research and practice frontiers of domestic perioperative analgesia, this working group has reached a consensus on several key domain—including the application regimens of NSAIDs for perioperative analgesia, drug interactions, and precautions as well as prevention strategies in special populations—yielding 12 definitive recommendations. This consensus aims to provide guidance for the standardized selection and application of NSAIDs for perioperative analgesia, and to further promote the rational, safe, and effective use of NSAIDs.

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Publication Details

Journal
Journal of Anesthesia and Translational Medicine
Published
2026-08-24
DOI
https://doi.org/10.1016/j.jatmed.2026.07.004
Primary Topic
Cancer, Stress, Anesthesia, and Immune Response
Type
article
Field-Weighted Citation Impact
0.00

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article

Expert consensus on the application of nonsteroidal anti-inflammatory drugs for perioperative analgesia

Yingying Zhao, Fuhai Ji, Qian Lei, Zhongyuan Xia et al.
Journal of Anesthesia and Translational Medicine
Cancer, Stress, Anesthesia, and Immune Response
article

Expert consensus on the application of nonsteroidal anti-inflammatory drugs for perioperative analgesia

Yingying Zhao, Fuhai Ji, Qian Lei, Zhongyuan Xia, Shuai Zhao, Xiangdong Chen, Xuesheng Liu, Min Xie, Jianjun Yang, Cen Cheng, Bing Zhang, Yanhong Liu, Xuemin Song, Foquan Luo
article en

Abstract

Although nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in multimodal pain management under the concept of enhanced recovery after surgery (ERAS), adverse reactions and safety events caused by their unreasonable use have become increasingly prominent. Drawing on the latest literature and evidence-based medicine domestically and abroad, and based on the research and practice frontiers of domestic perioperative analgesia, this working group has reached a consensus on several key domain—including the application regimens of NSAIDs for perioperative analgesia, drug interactions, and precautions as well as prevention strategies in special populations—yielding 12 definitive recommendations. This consensus aims to provide guidance for the standardized selection and application of NSAIDs for perioperative analgesia, and to further promote the rational, safe, and effective use of NSAIDs.

Journal of Anesthesia and Translational MedicineVol. 5(3)
Union Hospital (HK), University of Electronic Science and Technology of China (CN), Harbin Medical University (CN), Anhui Medical University (CN), Wuhan University (CN), Soochow University (CN), Zhongnan Hospital of Wuhan University (CN), Second Affiliated Hospital of Harbin Medical University (CN), First Affiliated Hospital of Anhui Medical University (CN), Renmin Hospital of Wuhan University (CN), First Affiliated Hospital of Soochow University (CN), First Affiliated Hospital of Zhengzhou University (CN), Hangzhou Medical College (CN), Huazhong University of Science and Technology (CN)
National Natural Science Foundation of China, Zhengzhou University
Good health and well-being
Openalex Percentile: Top 9%
Cancer, Stress, Anesthesia, and Immune Response
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