A null finding is not a negative finding: intramuscular penicillin prophylaxis and the perils of underpowered inference in mild rheumatic heart disease

To the Editor,The question of whether adults with mild rheumatic heart disease (RHD) require ongoing intramuscular penicillin prophylaxis is one of genuine clinical urgency, particularly as echocar...

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Publication Details

Journal
Acta cardiologica. Supplementum
Published
2026-08-24
DOI
https://doi.org/10.1080/00015385.2026.2722414
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A null finding is not a negative finding: intramuscular penicillin prophylaxis and the perils of underpowered inference in mild rheumatic heart disease

Minahil Iqbal
Acta cardiologica. Supplementum
Streptococcal Infections and Treatments
article

A null finding is not a negative finding: intramuscular penicillin prophylaxis and the perils of underpowered inference in mild rheumatic heart disease

Minahil Iqbal
article en

Abstract

To the Editor,The question of whether adults with mild rheumatic heart disease (RHD) require ongoing intramuscular penicillin prophylaxis is one of genuine clinical urgency, particularly as echocar...

Acta cardiologica. Supplementum
Iqra University (PK)
Openalex Percentile: Top 7%
Streptococcal Infections and Treatments
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A null finding is not a negative finding: intramuscular penicillin prophylaxis and the perils of underpowered inference in mild rheumatic heart disease — Minahil Iqbal · Acta cardiologica. Supplementum (2026) | TGRS Research Map | TGRS