Quantum Coherence in Microtubules: A Physical Substrate for Consciousness — E8 Intelligence Research

FINDING: Microtubule quantum coherence research suggests a physical substrate for consciousness via quantum effects in brain microtubules, with recent simulations and studies claiming evidence for quantum excitations traveling along these structures. | MATH: Microtubules are hollow cylinders ~25 nm diameter, composed of tubulin dimers arranged in a hexagonal lattice (13 protofilaments typically, giving a 13-fold rotational symmetry). The key mathematical structure is the tubulin dimer lattice — a 2D hexagonal lattice with a lattice constant ~8 nm (αβ-tubulin dimer length ~8 nm). Quantum coherence timescales are proposed via Fröhlich condensation (coherent dipole oscillations at ~THz frequencies, ~10^12 Hz), with energy gaps ~1 meV (thermal energy kT at 300K ≈ 25.9 meV, so coherence requires energy separation ΔE >> kT or shielding). The Orch-OR model invokes quantum superposition of tubulin states with collapse via objective reduction (OR) — the gravity-induced collapse time τ ≈ ħ/E_G, Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-08-24
DOI
https://doi.org/10.5281/zenodo.22075768
Primary Topic
Microtubule and mitosis dynamics
Type
preprint
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preprint

Quantum Coherence in Microtubules: A Physical Substrate for Consciousness — E8 Intelligence Research

Andrew Stewart Caldin
Zenodo (CERN European Organization for Nuclear Research)
Microtubule and mitosis dynamics
preprint

Quantum Coherence in Microtubules: A Physical Substrate for Consciousness — E8 Intelligence Research

Andrew Stewart Caldin
preprint en

Abstract

FINDING: Microtubule quantum coherence research suggests a physical substrate for consciousness via quantum effects in brain microtubules, with recent simulations and studies claiming evidence for quantum excitations traveling along these structures. | MATH: Microtubules are hollow cylinders ~25 nm diameter, composed of tubulin dimers arranged in a hexagonal lattice (13 protofilaments typically, giving a 13-fold rotational symmetry). The key mathematical structure is the tubulin dimer lattice — a 2D hexagonal lattice with a lattice constant ~8 nm (αβ-tubulin dimer length ~8 nm). Quantum coherence timescales are proposed via Fröhlich condensation (coherent dipole oscillations at ~THz frequencies, ~10^12 Hz), with energy gaps ~1 meV (thermal energy kT at 300K ≈ 25.9 meV, so coherence requires energy separation ΔE >> kT or shielding). The Orch-OR model invokes quantum superposition of tubulin states with collapse via objective reduction (OR) — the gravity-induced collapse time τ ≈ ħ/E_G, Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

Zenodo (CERN European Organization for Nuclear Research)
Microtubule and mitosis dynamics
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