Supporting upper limb movements with a soft robot after a brachial plexus injury

Brachial plexus injury causes severe arm weakness, forcing patients to rely on compensatory movements for daily activities. Most robotic solutions target isolated elbow or hand function, whereas multi-joint assistance remains limited. Here we show that a soft wearable exosuit providing shoulder and elbow assistance through pneumatic actuation and inertial sensing improves arm function in 14 adults with chronic traumatic brachial plexus injury, including six with complete lesions and ten after nerve transfer surgery. In single-session testing, the device increases active range of motion ( + 80-180%) and static endurance ( + 160%), reduces perceived effort near to zero, lowers muscle activity (−30-60%) and fatigue, and preserves moderate-to-high sense of agency and good satisfaction. In a subset of four participants, functional task performance improves (Action Research Arm Test +4.5 points on average) and movements become smoother and less compensatory. These results show that soft multi-joint assistance can provide immediate benefits during use and support further development of wearable assistance for people with brachial plexus injury. Brachial plexus injury causes severe arm weakness, forcing patients to rely on compensatory movements for daily activities. Here, the authors develop an exosuit for shoulder and elbow assistance and demonstrate its ability to improve arm movement, reduce effort, and support daily tasks.

Authors

Institutions

Publication Details

Journal
Nature Communications
Published
2026-08-24
DOI
https://doi.org/10.1038/s41467-026-76824-6
Primary Topic
Stroke Rehabilitation and Recovery
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Supporting upper limb movements with a soft robot after a brachial plexus injury

Paolo Titolo, Tommaso Proietti, Silvestro Micera, Jacopo Carpaneto et al.
Nature Communications
Stroke Rehabilitation and Recovery
article

Supporting upper limb movements with a soft robot after a brachial plexus injury

Paolo Titolo, Tommaso Proietti, Silvestro Micera, Jacopo Carpaneto, Daniele Filippo Mauceri, Roberto Ferroni, Vittoria Aglietta
article en

Abstract

Brachial plexus injury causes severe arm weakness, forcing patients to rely on compensatory movements for daily activities. Most robotic solutions target isolated elbow or hand function, whereas multi-joint assistance remains limited. Here we show that a soft wearable exosuit providing shoulder and elbow assistance through pneumatic actuation and inertial sensing improves arm function in 14 adults with chronic traumatic brachial plexus injury, including six with complete lesions and ten after nerve transfer surgery. In single-session testing, the device increases active range of motion ( + 80-180%) and static endurance ( + 160%), reduces perceived effort near to zero, lowers muscle activity (−30-60%) and fatigue, and preserves moderate-to-high sense of agency and good satisfaction. In a subset of four participants, functional task performance improves (Action Research Arm Test +4.5 points on average) and movements become smoother and less compensatory. These results show that soft multi-joint assistance can provide immediate benefits during use and support further development of wearable assistance for people with brachial plexus injury. Brachial plexus injury causes severe arm weakness, forcing patients to rely on compensatory movements for daily activities. Here, the authors develop an exosuit for shoulder and elbow assistance and demonstrate its ability to improve arm movement, reduce effort, and support daily tasks.

Nature Communications
Vita-Salute San Raffaele University (IT), Scuola Superiore Sant'Anna (IT), CTO Hospital (IT), École Polytechnique Fédérale de Lausanne (CH), University of Turin (IT)
Openalex Percentile: Top 13%
Stroke Rehabilitation and Recovery
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Supporting upper limb movements with a soft robot after a brachial plexus injury — Paolo Titolo, Tommaso Proietti, et al. · Nature Communications (2026) | TGRS Research Map | TGRS