Persistent foetal vasculature with anterior retinal extension, anterior vitreous extension, and morning glory syndrome: a rare constellation of congenital ocular developmental anomalies

This case report describes a rare combination of persistent foetal vasculature, morning glory syndrome, anterior retinal extension, and anterior vitreous extension in a 3-month-old baby with congenital cataract. This constellation complicates clinical evaluation, surgical management, and functional and anatomical outcomes. The present case report highlights the significance of identifying multiple abnormalities before undertaking congenital cataract surgery. Families must be informed about these components before surgery. This rare constellation of congenital ocular developmental anomalies broadens the recognized phenotypic spectrum of ocular dysgenesis. As a single case report, this clinical observation should be regarded as hypothesis-generating and requires confirmation in additional well-characterized cases.

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Publication Details

Journal
BMC Ophthalmology
Published
2026-08-24
DOI
https://doi.org/10.1186/s12886-026-05258-x
Primary Topic
Retinal and Macular Surgery
Type
article
Field-Weighted Citation Impact
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article

Persistent foetal vasculature with anterior retinal extension, anterior vitreous extension, and morning glory syndrome: a rare constellation of congenital ocular developmental anomalies

Omer Othman Abdullah
BMC Ophthalmology
Retinal and Macular Surgery
article

Persistent foetal vasculature with anterior retinal extension, anterior vitreous extension, and morning glory syndrome: a rare constellation of congenital ocular developmental anomalies

Omer Othman Abdullah
article en

Abstract

This case report describes a rare combination of persistent foetal vasculature, morning glory syndrome, anterior retinal extension, and anterior vitreous extension in a 3-month-old baby with congenital cataract. This constellation complicates clinical evaluation, surgical management, and functional and anatomical outcomes. The present case report highlights the significance of identifying multiple abnormalities before undertaking congenital cataract surgery. Families must be informed about these components before surgery. This rare constellation of congenital ocular developmental anomalies broadens the recognized phenotypic spectrum of ocular dysgenesis. As a single case report, this clinical observation should be regarded as hypothesis-generating and requires confirmation in additional well-characterized cases.

BMC Ophthalmology
Retina Clinic (BR)
Zero hunger
Openalex Percentile: Top 10%
Retinal and Macular Surgery
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Persistent foetal vasculature with anterior retinal extension, anterior vitreous extension, and morning glory syndrome: a rare constellation of congenital ocular developmental anomalies — Omer Othman Abdullah · BMC Ophthalmology (2026) | TGRS Research Map | TGRS