Screening of illegally adulterated oxyphenisatin and phenolphthalein derivatives in weight-loss foods via UPLC-QTrap precursor ion scanning coupled with HRMS confirmation

). Application of this method to 50 samples of commercial weight-loss foods led to the identification of a novel, illegally added oxyphenisatin analog in soft candy. To confirm the unknown compound, a post-hydrolysis comparison substance verification strategy was implemented, supported by high-resolution mass spectrometry (HRMS) for molecular formula confirmation.

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Publication Details

Journal
Food Additives & Contaminants Part A
Published
2026-08-21
DOI
https://doi.org/10.1080/19440049.2026.2693982
Primary Topic
Pharmaceutical Quality and Counterfeiting
Type
article
Field-Weighted Citation Impact
0.00
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article

Screening of illegally adulterated oxyphenisatin and phenolphthalein derivatives in weight-loss foods via UPLC-QTrap precursor ion scanning coupled with HRMS confirmation

Jun Yang, Ziyan Hu, Qingqing Sun, Liang Yuan et al.
Food Additives & Contaminants Part A
Pharmaceutical Quality and Counterfeiting
article

Screening of illegally adulterated oxyphenisatin and phenolphthalein derivatives in weight-loss foods via UPLC-QTrap precursor ion scanning coupled with HRMS confirmation

Jun Yang, Ziyan Hu, Qingqing Sun, Liang Yuan, Zhi Ma, Huimin Chen, Wenting Liao, Dan Li
article en

Abstract

). Application of this method to 50 samples of commercial weight-loss foods led to the identification of a novel, illegally added oxyphenisatin analog in soft candy. To confirm the unknown compound, a post-hydrolysis comparison substance verification strategy was implemented, supported by high-resolution mass spectrometry (HRMS) for molecular formula confirmation.

Food Additives & Contaminants Part A
China Pharmaceutical University (CN), Daiseung Medics (South Korea) (KR), Immune Regulation (United Kingdom) (GB), ZheJiang Institute For Food and Drug Control (CN)
Openalex Percentile: Top 7%
Pharmaceutical Quality and Counterfeiting
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Screening of illegally adulterated oxyphenisatin and phenolphthalein derivatives in weight-loss foods via UPLC-QTrap precursor ion scanning coupled with HRMS confirmation — Jun Yang, Ziyan Hu, et al. · Food Additives & Contaminants Part A (2026) | TGRS Research Map | TGRS