Maternal Syphilis of Unknown Duration: Birth Outcomes in an Immediate Test-and-Treat Cohort often Receiving Fewer than Three Doses of Benzathine Penicillin G
In a South African antenatal cohort, an immediate test-and-treat model for syphilis of unknown duration showed that adverse birth outcomes-including stillbirth and preterm birth-were similar between women without syphilis and those treated with penicillin, regardless of completion of the three-dose regimen. Further studies are needed to evaluate optimal treatment strategies in pregnancy.
Authors
- Chibuzor M. Babalola (ORCID: https://orcid.org/0000-0003-3762-1620)
- Christina A. Muzny (ORCID: https://orcid.org/0000-0002-4005-3858)
- Andrew Medina‐Marino (ORCID: https://orcid.org/0000-0002-0095-4141)
- Remco P. H. Peters (ORCID: https://orcid.org/0000-0003-2124-7275)
- Christopher M. Taylor (ORCID: https://orcid.org/0000-0002-7983-5275)
- Mandisa M. Mdingi
- Msindisi Gqirana
- Jeffrey D Klausner
Institutions
- University of Southern California (US)
- University of Alabama at Birmingham (US)
- Foundation for Professional Development (ZA)
- University of Pretoria (ZA)
- Louisiana State University Health Sciences Center New Orleans (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Sexually Transmitted Diseases
- Published
- 2026-08-21
- DOI
- https://doi.org/10.1097/olq.0000000000002396
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00