Engineering Parameter Window for Filament Formation and Early-Stage Evolution in Embedded Printing of Gelatin/Alginate Hydrogels Within Carbomer Support Baths
Embedded 3D printing of hydrophilic hydrogels in aqueous support baths often suffers from filament deformation, positional deviation, and diffusion before complete cross-linking, while practical parameter-selection guidelines for specific material systems remain limited. In this work, an integrated engineering evaluation method was developed to characterize filament formation and early-stage evolution during embedded printing of gelatin/sodium alginate inks in Carbomer support baths. Filament quality was assessed using cross-sectional geometry, contour irregularity, deposition position, and early-stage diffusion ratio. The effects of printing kinematics and material rheology are systematically examined to establish a practical process window for this hydrophilic ink–bath system. The results show that the speed ratio between substrate and ink is a primary factor controlling filament geometry and deposition position, and a ratio close to 1 yields the most balanced cross-sectional morphology without position shift from the printed nozzle. Ink with high viscosity maintains contour irregularity within a narrow range of 0.005–0.009 and suppresses early diffusion, whereas a support bath with high viscosity and ink with high viscosity combination further slows diffusional evolution by about 70%. Based on the identified process window, several three-dimensional hydrogel structures were fabricated successfully. The proposed workflow provides a practical route for process evaluation and parameter selection in hydrophilic embedded printing, especially for continuous filament and tubular structures, and offers engineering guidance for bio-soft material fabrication in applications.
Authors
- Yuanfen Chen (ORCID: https://orcid.org/0000-0003-1111-054X)
- Hui You (ORCID: https://orcid.org/0000-0002-6821-6188)
- Lin Lin (ORCID: https://orcid.org/0000-0001-7853-2558)
- Wang Tang (ORCID: https://orcid.org/0009-0001-3542-5143)
- Jinhu Wang
- Yong Wang
- Zihang Yan
- Jinwei Li
- Huansi Mo
Institutions
- Guangxi University (CN)
Publication Details
- Journal
- Gels
- Published
- 2026-08-21
- DOI
- https://doi.org/10.3390/gels12080749
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangxi Province