Jasmonic Acid and Salicylic Acid in Regulating Plant Cadmium Accumulation and Tolerance: Mechanisms and Crosstalk

Cadmium (Cd) is a highly toxic non-essential heavy metal that severely impairs plant growth, compromises crop yield and quality, and threatens food safety and human health. Jasmonic acid (JA) and salicylic acid (SA) are well-characterized endogenous phytohormones that serve as central regulators in modulating plant adaptive responses to Cd stress. This review comprehensively synthesizes current knowledge on the involvement of JA and SA in regulating Cd accumulation and tolerance in plants, including their Cd-induced biosynthetic dynamics and signaling transduction pathways, as well as their functions in restricting Cd uptake and translocation, modulating chelation and sequestration, reinforcing antioxidant defense systems and protecting photosynthetic apparatus. Moreover, we analyze the antagonistic and synergistic crosstalk between JA and SA, and discuss how this interplay shapes Cd resilience in plants. Finally, the application potential of JA and SA in developing Cd-safe crops and phytoremediation in Cd-contaminated farmland is explored. This review provides a systematic analysis of the regulatory roles of JA and SA in plant responses to Cd stress, along with an in-depth discussion of their crosstalk. These insights contribute to the rational development of hormone-based breeding strategies for Cd-safe crops and the optimization of agronomic management practices.