Parallel spatial cross attention ensembled deep learning model for lung cancer diagnosis and classification using computed tomography images

Lung cancer is considered one of the deadliest cancer types, which affects the respiratory system severely. Globally, the rate of morality is increasing every year due to the lack of diagnosis of lung cancer at its early stage. Thus, lung cancer detection and classification are essential to decrease mortality and increase the probability of patient survival. However, the traditional lung cancer classification techniques possessed the drawbacks of poor generalization, high false positives, higher computational complexities, higher memory consumption and so on. Hence, this research proposes a Parallel Spatial Cross Attention ensemble Bidirectional long short-Term Memory (PSCABTM) model to classify lung cancer by overcoming the shortcomings of the existing models. The Parallel Spatial Cross Attention (PSCA) mechanism can capture the fine-grained features and long-range dependencies, which leads to accurate classification results. Moreover, the extraction of Deep Radiomics Transformer Features (DRTF) minimizes the computational complexity, resulting in lower memory usage and a faster training process. Additionally, the PSCABTM model learns hierarchical features in both forward and backward directions, which facilitates overcoming the limitation of traditional techniques and leads to better classification. According to the experimental results, the proposed model outperforms existing methods and attains F1-score, accuracy, specificity, recall, and precision of 99.20%, 99.20%, 98.60%, 99.76% and 98.15% using the LUNA16 dataset, respectively.

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Publication Details

Journal
Scientific Reports
Published
2026-08-21
DOI
https://doi.org/10.1038/s41598-026-66729-1
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
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article

Parallel spatial cross attention ensembled deep learning model for lung cancer diagnosis and classification using computed tomography images

Shaik Sikindar, Vahiduddin Shariff, Patchava Lakshmi, Geetha Reddy Yenna et al.
Scientific Reports
Lung Cancer Diagnosis and Treatment
article

Parallel spatial cross attention ensembled deep learning model for lung cancer diagnosis and classification using computed tomography images

Shaik Sikindar, Vahiduddin Shariff, Patchava Lakshmi, Geetha Reddy Yenna, G. ArunKumar
article en

Abstract

Lung cancer is considered one of the deadliest cancer types, which affects the respiratory system severely. Globally, the rate of morality is increasing every year due to the lack of diagnosis of lung cancer at its early stage. Thus, lung cancer detection and classification are essential to decrease mortality and increase the probability of patient survival. However, the traditional lung cancer classification techniques possessed the drawbacks of poor generalization, high false positives, higher computational complexities, higher memory consumption and so on. Hence, this research proposes a Parallel Spatial Cross Attention ensemble Bidirectional long short-Term Memory (PSCABTM) model to classify lung cancer by overcoming the shortcomings of the existing models. The Parallel Spatial Cross Attention (PSCA) mechanism can capture the fine-grained features and long-range dependencies, which leads to accurate classification results. Moreover, the extraction of Deep Radiomics Transformer Features (DRTF) minimizes the computational complexity, resulting in lower memory usage and a faster training process. Additionally, the PSCABTM model learns hierarchical features in both forward and backward directions, which facilitates overcoming the limitation of traditional techniques and leads to better classification. According to the experimental results, the proposed model outperforms existing methods and attains F1-score, accuracy, specificity, recall, and precision of 99.20%, 99.20%, 98.60%, 99.76% and 98.15% using the LUNA16 dataset, respectively.

Scientific Reports
Vignan's Foundation for Science, Technology & Research (IN), University College for Women (IN), Indian Institute of Oil Palm Research (IN), Institute of Chartered Financial Analysts of India (IN)
Good health and well-being
Openalex Percentile: Top 11%
Lung Cancer Diagnosis and Treatment
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