Information matters, but cues are dangerous: a comparative evaluation of three multimodal AI chatbots in oral and maxillofacial radiology

OBJECTIVES: To compare the diagnostic performance of three multimodal AI chatbots on oral and maxillofacial radiographic images and to examine how additional information, delivery mode, and user-suggested diagnoses affect accuracy. METHODS: Three AI chatbots (GPT-5.1, Gemini 3 Flash, Claude Opus 4.7) were tested on 90 cases comprising normal controls, osteomyelitis, and benign jaw lesions. Inputs were combinations of a panoramic image, a cropped panoramic image, an axial CBCT image or a text-based cue. Inputs were delivered all at once or sequentially. Accuracy was scored at category and specific-diagnosis levels using non-parametric tests with false-discovery-rate correction. RESULTS: With the panoramic image alone, accuracy for diseased cases was low (0-60%) but rose to as high as 38-92% in each model's best condition with added information. A cropped image was the most consistently beneficial additional visual input, whereas an axial CBCT image provided less improvement. GPT-5.1 recognised normal cases well but missed lesions, Gemini 3 was sensitive but less specific, and Claude 4.7 defaulted to benign diagnoses. Correct verbal cues increased accuracy, whereas a misleading cue caused decline. Gemini 3 accepted a false benign suggestion in 96% of cases it had initially classified as normal. For benign lesions, specific-diagnosis accuracy was almost half of category-level accuracy. CONCLUSIONS: Accuracy was strongly affected by model choice, information type and user-suggested diagnoses, but no model reached a level that would be acceptable for clinical use. ADVANCES IN KNOWLEDGE: This multi-model comparison isolates the effects of information type, delivery mode, and sycophancy in oral and maxillofacial radiology.

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Publication Details

Journal
Dentomaxillofacial Radiology
Published
2026-08-20
DOI
https://doi.org/10.1093/dmfr/twag061
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
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article

Information matters, but cues are dangerous: a comparative evaluation of three multimodal AI chatbots in oral and maxillofacial radiology

Chang‐Ki Min
Dentomaxillofacial Radiology
Artificial Intelligence in Healthcare and Education
article

Information matters, but cues are dangerous: a comparative evaluation of three multimodal AI chatbots in oral and maxillofacial radiology

Chang‐Ki Min
article en

Abstract

OBJECTIVES: To compare the diagnostic performance of three multimodal AI chatbots on oral and maxillofacial radiographic images and to examine how additional information, delivery mode, and user-suggested diagnoses affect accuracy. METHODS: Three AI chatbots (GPT-5.1, Gemini 3 Flash, Claude Opus 4.7) were tested on 90 cases comprising normal controls, osteomyelitis, and benign jaw lesions. Inputs were combinations of a panoramic image, a cropped panoramic image, an axial CBCT image or a text-based cue. Inputs were delivered all at once or sequentially. Accuracy was scored at category and specific-diagnosis levels using non-parametric tests with false-discovery-rate correction. RESULTS: With the panoramic image alone, accuracy for diseased cases was low (0-60%) but rose to as high as 38-92% in each model's best condition with added information. A cropped image was the most consistently beneficial additional visual input, whereas an axial CBCT image provided less improvement. GPT-5.1 recognised normal cases well but missed lesions, Gemini 3 was sensitive but less specific, and Claude 4.7 defaulted to benign diagnoses. Correct verbal cues increased accuracy, whereas a misleading cue caused decline. Gemini 3 accepted a false benign suggestion in 96% of cases it had initially classified as normal. For benign lesions, specific-diagnosis accuracy was almost half of category-level accuracy. CONCLUSIONS: Accuracy was strongly affected by model choice, information type and user-suggested diagnoses, but no model reached a level that would be acceptable for clinical use. ADVANCES IN KNOWLEDGE: This multi-model comparison isolates the effects of information type, delivery mode, and sycophancy in oral and maxillofacial radiology.

Dentomaxillofacial Radiology
Jeonbuk National University Hospital (KR), Jeonbuk National University (KR)
Openalex Percentile: Top 13%
Artificial Intelligence in Healthcare and Education
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