Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage—A German Nationwide Survey

BACKGROUND: Delayed cerebral ischemia (DCI) remains a major cause of morbidity after aneurysmal subarachnoid hemorrhage (aSAH). Induced hypertension (IH) is frequently used to improve cerebral perfusion in patients with DCI, with current practice primarily supported by observational evidence with inconsistent guideline recommendations. We conducted a nationwide survey to assess current institutional approaches to IH in the management of DCI after aSAH in Germany. METHODS: An 11-item web-based questionnaire was distributed via LimeSurvey® between May and October 2025 to neurological and neurosurgical departments in Germany involved in the treatment of aSAH. The survey assessed institutional approaches to IH, monitoring and imaging strategies, and DCI treatment. RESULTS: Overall, 60/132 departments (45%) responded. IH was used by 56/59 departments (95%), predominantly in patients with suspected DCI (52/59, 88%). MAP-guided therapy was the most commonly applied IH strategy (64%), although hemodynamic targets varied substantially between departments. Noradrenaline was the primary vasopressor used for IH (98%). Transcranial doppler (TCD) ultrasonography was the predominant monitoring modality for DCI detection (93%), whereas advanced neuromonitoring techniques were used less frequently. Computed tomography (CT) perfusion (88%) and CT angiography (79%) were the most commonly applied imaging modalities in suspected DCI. IH alone (47%) or combined with intraarterial spasmolysis (36%) represented the leading first-line therapeutic approaches. CONCLUSIONS: IH remains a central component of DCI management after aSAH in Germany. Considerable variability regarding hemodynamic targets, monitoring strategies, imaging protocols, and therapeutic strategies highlights the absence of standardized evidence-based treatment approaches.

Authors

Institutions

Publication Details

Journal
Neurocritical Care
Published
2026-08-20
DOI
https://doi.org/10.1007/s12028-026-02635-8
Primary Topic
Intracranial Aneurysms: Treatment and Complications
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage—A German Nationwide Survey

Tammam Abboud, Silvia Hernández‐Durán, Beate Kranawetter
Neurocritical Care
Intracranial Aneurysms: Treatment and Complications
article

Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage—A German Nationwide Survey

Tammam Abboud, Silvia Hernández‐Durán, Beate Kranawetter
article en

Abstract

BACKGROUND: Delayed cerebral ischemia (DCI) remains a major cause of morbidity after aneurysmal subarachnoid hemorrhage (aSAH). Induced hypertension (IH) is frequently used to improve cerebral perfusion in patients with DCI, with current practice primarily supported by observational evidence with inconsistent guideline recommendations. We conducted a nationwide survey to assess current institutional approaches to IH in the management of DCI after aSAH in Germany. METHODS: An 11-item web-based questionnaire was distributed via LimeSurvey® between May and October 2025 to neurological and neurosurgical departments in Germany involved in the treatment of aSAH. The survey assessed institutional approaches to IH, monitoring and imaging strategies, and DCI treatment. RESULTS: Overall, 60/132 departments (45%) responded. IH was used by 56/59 departments (95%), predominantly in patients with suspected DCI (52/59, 88%). MAP-guided therapy was the most commonly applied IH strategy (64%), although hemodynamic targets varied substantially between departments. Noradrenaline was the primary vasopressor used for IH (98%). Transcranial doppler (TCD) ultrasonography was the predominant monitoring modality for DCI detection (93%), whereas advanced neuromonitoring techniques were used less frequently. Computed tomography (CT) perfusion (88%) and CT angiography (79%) were the most commonly applied imaging modalities in suspected DCI. IH alone (47%) or combined with intraarterial spasmolysis (36%) represented the leading first-line therapeutic approaches. CONCLUSIONS: IH remains a central component of DCI management after aSAH in Germany. Considerable variability regarding hemodynamic targets, monitoring strategies, imaging protocols, and therapeutic strategies highlights the absence of standardized evidence-based treatment approaches.

Neurocritical Care
University of Rostock (DE), University of Göttingen (DE)
Georg-August-Universität Göttingen
Good health and well-being
Openalex Percentile: Top 10%
Intracranial Aneurysms: Treatment and Complications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.