Multimodal imaging and AI in brain tumor surgery: current tools and emerging integration

Brain tumors remain among the most challenging malignancies, necessitating advances in diagnostic accuracy and treatment precision. Integrated multimodal surgical platforms combining structural, functional, and molecular data are transforming neuro-oncology by improving surgical planning, intraoperative guidance, and patient monitoring. This perspective reviews current and emerging imaging modalities including optical techniques and AI-integrated platforms, while discussing their integration within unified clinical workflows that may advance personalized brain tumor care and surgical outcomes.

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Publication Details

Journal
npj Biomedical Innovations.
Published
2026-08-20
DOI
https://doi.org/10.1038/s44385-026-00105-6
Primary Topic
Optical Imaging and Spectroscopy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Multimodal imaging and AI in brain tumor surgery: current tools and emerging integration

Thomas A. Nelson, David Miller, James Battiste, Diogo Pinheiro Cordeiro et al.
npj Biomedical Innovations.
Optical Imaging and Spectroscopy Techniques
article

Multimodal imaging and AI in brain tumor surgery: current tools and emerging integration

Thomas A. Nelson, David Miller, James Battiste, Diogo Pinheiro Cordeiro, Christopher S. Graffeo
article en

Abstract

Brain tumors remain among the most challenging malignancies, necessitating advances in diagnostic accuracy and treatment precision. Integrated multimodal surgical platforms combining structural, functional, and molecular data are transforming neuro-oncology by improving surgical planning, intraoperative guidance, and patient monitoring. This perspective reviews current and emerging imaging modalities including optical techniques and AI-integrated platforms, while discussing their integration within unified clinical workflows that may advance personalized brain tumor care and surgical outcomes.

npj Biomedical Innovations.Vol. 3(1)
University of California, San Francisco (US), Oklahoma City University (US), Neurological Surgery (US), University of Oklahoma (US)
American Cancer Society, University of Oklahoma, Stephenson Cancer Center
Openalex Percentile: Top 10%
Optical Imaging and Spectroscopy Techniques
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Multimodal imaging and AI in brain tumor surgery: current tools and emerging integration — Thomas A. Nelson, David Miller, et al. · npj Biomedical Innovations. (2026) | TGRS Research Map | TGRS