Comparative Performance of 18F-FDG PET/CT and 68Ga-FAPI PET/CT in TENIS Syndrome in Treated Differentiated Thyroid Carcinoma
Objectives: Ga)-fibroblast activation protein inhibitor (FAPI) PET/CT, which targets the tumor stroma, represents a promising new alternative. This study directly compared the lesion detection capabilities of both tracers in patients with TENIS. Methods: I therapy, imaging correlation or progression, and clinical progression methods. Results: Ga-FAPI-positive. Distant metastases (lung and bone) showed similar detection rates. Conclusion: F-FDG PET/CT remains the preferred imaging modality for comprehensive disease evaluation in patients with radioactive iodine-refractory DTC.
Authors
- Parvathy Pavithran
- Manjit Sarma (ORCID: https://orcid.org/0000-0002-4086-4423)
- Sanjana Sajeev
- Usha Menon (ORCID: https://orcid.org/0000-0003-3708-1732)
- Awiral Saxena
- Padma Subramanyam
- Jayantilal Bhagirath Bhad
- B. Venkata Sai Ram Reddy
- Ramkesh R.
- Shanmuga Sundaram P
Institutions
- Amrita Institute of Medical Sciences and Research Centre (IN)
Publication Details
- Journal
- Molecular Imaging and Radionuclide Therapy
- Published
- 2026-08-18
- DOI
- https://doi.org/10.4274/mirt.galenos.2026.80037
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00