Advancing minimally invasive precision surgery in large open cavities with robotic flexible endoscopy

Flexible robots hold great promise for enhancing minimally invasive surgery (MIS) by providing superior dexterity, precise control, and safe tissue interaction. Yet, translating these advantages into endoscopic interventions in large open cavities remains challenging. The lack of anatomical constraints and the inherent flexibility of such devices complicate their control, and the limited field of view of endoscopes restricts situational awareness. We present a robotic platform designed to overcome these challenges and demonstrate its potential in fetoscopic laser coagulation-a complex MIS procedure typically performed only by highly experienced surgeons. Our system combines a magnetically actuated flexible endoscope with teleoperated and semi-autonomous navigation capabilities for performing targeted laser ablations. To enhance surgical awareness, the platform reconstructs real-time mosaics of the endoscopic scene, providing an extended and continuous visual context. The ability of this system to address the key limitations of MIS in open spaces is validated in vivo in an ovine model.

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Publication Details

Journal
Science Robotics
Published
2026-09-16
DOI
https://doi.org/10.1126/scirobotics.aed1470
Primary Topic
Soft Robotics and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Advancing minimally invasive precision surgery in large open cavities with robotic flexible endoscopy

Miriam Weisskopf, Ueli Moehrlen, Bradley J. Nelson, Alexandre Mesot et al.
Science Robotics
Soft Robotics and Applications
article

Advancing minimally invasive precision surgery in large open cavities with robotic flexible endoscopy

Miriam Weisskopf, Ueli Moehrlen, Bradley J. Nelson, Alexandre Mesot, Nicole Ochsenbein‐Kölble, Quentin Boehler, Michelle Mattille
article en

Abstract

Flexible robots hold great promise for enhancing minimally invasive surgery (MIS) by providing superior dexterity, precise control, and safe tissue interaction. Yet, translating these advantages into endoscopic interventions in large open cavities remains challenging. The lack of anatomical constraints and the inherent flexibility of such devices complicate their control, and the limited field of view of endoscopes restricts situational awareness. We present a robotic platform designed to overcome these challenges and demonstrate its potential in fetoscopic laser coagulation-a complex MIS procedure typically performed only by highly experienced surgeons. Our system combines a magnetically actuated flexible endoscope with teleoperated and semi-autonomous navigation capabilities for performing targeted laser ablations. To enhance surgical awareness, the platform reconstructs real-time mosaics of the endoscopic scene, providing an extended and continuous visual context. The ability of this system to address the key limitations of MIS in open spaces is validated in vivo in an ovine model.

Science RoboticsVol. 11(118)
University of Zurich (CH), ETH Zurich (CH), University Hospital of Zurich (CH), University Children's Hospital Zurich (CH)
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Innovation and Technology Commission
Openalex Percentile: Top 32%
Soft Robotics and Applications
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