Targeting the Oral Mucosa With Egg Protein Effectively Prevents Egg Allergy in Mice
Summary Oral ovalbumin administration prevents epicutaneously‐induced egg allergy by suppressing Tfh and B cells and IgE. This prophylactic oral ovalbumin abolishes antigen‐specific IL‐4 and IL‐13 production in skin‐draining lymph nodes.
Authors
- Ryoji Kawakami (ORCID: https://orcid.org/0000-0003-2253-4559)
- Hirohito Kita (ORCID: https://orcid.org/0000-0002-6854-2936)
- Norihisa Mikami (ORCID: https://orcid.org/0000-0001-6360-5363)
- Takumi Tsuji (ORCID: https://orcid.org/0000-0002-9931-1866)
- Yuya Yoshida (ORCID: https://orcid.org/0000-0001-7410-6359)
- Hiroki Urakawa
- Mina Iwata
- Yusei Kiuchi
- Hikaru Fuchita
- Ryohei Shibao
Institutions
- Setsunan University (JP)
- Mayo Clinic (US)
- Kyoto University (JP)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- The University of Osaka (JP)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-08-17
- DOI
- https://doi.org/10.1111/cea.70422
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00