Implementation of bedside and intraoperative neurophysiological monitoring in the diagnosis of functional neurological symptom disorder following spinal surgery: illustrative case

BACKGROUND: Intraoperative somatosensory evoked potentials (SSEPs) are routinely used during spine surgery to assess the integrity of white matter pathways and identify potential neurological injury. Their use as a bedside diagnostic adjunct for unexplained postoperative neurological deficits, particularly when functional neurological disorder (FND) is suspected, has not been well described. OBSERVATIONS: A 53-year-old woman developed profound lower extremity weakness and sensory loss after L3-5 decompression and fusion despite stable intraoperative neuromonitoring and imaging findings that did not explain her deficits. Bedside SSEPs remained normal and comparable to intraoperative recordings. Subsequent revision surgery also demonstrated stable SSEPs and robust transcranial motor evoked potentials. Together with inconsistent examination findings and preserved movement when distracted, these results supported a multidisciplinary diagnosis of FND. LESSONS: Bedside SSEPs may provide objective evidence of preserved sensory pathway function in patients with unexplained postoperative neurological deficits and may assist in distinguishing functional symptoms from structural injury. https://thejns.org/doi/10.3171/CASE251006.

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Journal
Journal of Neurosurgery Case Lessons
Published
2026-08-17
DOI
https://doi.org/10.3171/case251006
Primary Topic
Intraoperative Neuromonitoring and Anesthetic Effects
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article
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article

Implementation of bedside and intraoperative neurophysiological monitoring in the diagnosis of functional neurological symptom disorder following spinal surgery: illustrative case

James Mooney, Nitin Agarwal, Ayesha Akbar Waheed, William Rabon et al.
Journal of Neurosurgery Case Lessons
Intraoperative Neuromonitoring and Anesthetic Effects
article

Implementation of bedside and intraoperative neurophysiological monitoring in the diagnosis of functional neurological symptom disorder following spinal surgery: illustrative case

James Mooney, Nitin Agarwal, Ayesha Akbar Waheed, William Rabon, Sirisha Nouduri, D. Kojo Hamilton, Qazi Zeeshan, Jeffrey Balzer, Hallie Triplett
article en

Abstract

BACKGROUND: Intraoperative somatosensory evoked potentials (SSEPs) are routinely used during spine surgery to assess the integrity of white matter pathways and identify potential neurological injury. Their use as a bedside diagnostic adjunct for unexplained postoperative neurological deficits, particularly when functional neurological disorder (FND) is suspected, has not been well described. OBSERVATIONS: A 53-year-old woman developed profound lower extremity weakness and sensory loss after L3-5 decompression and fusion despite stable intraoperative neuromonitoring and imaging findings that did not explain her deficits. Bedside SSEPs remained normal and comparable to intraoperative recordings. Subsequent revision surgery also demonstrated stable SSEPs and robust transcranial motor evoked potentials. Together with inconsistent examination findings and preserved movement when distracted, these results supported a multidisciplinary diagnosis of FND. LESSONS: Bedside SSEPs may provide objective evidence of preserved sensory pathway function in patients with unexplained postoperative neurological deficits and may assist in distinguishing functional symptoms from structural injury. https://thejns.org/doi/10.3171/CASE251006.

Journal of Neurosurgery Case LessonsVol. 12(7)
University of Pittsburgh (US), Virginia Commonwealth University (US), VA Pittsburgh Healthcare System (US), University of Pittsburgh Medical Center (US), Neurological Surgery (US)
Good health and well-being
Openalex Percentile: Top 7%
Intraoperative Neuromonitoring and Anesthetic Effects
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