Nonlinear multi-frequency electrical impedance tomography: An unfolded optimization approach

Multi-frequency Electrical Impedance Tomography (mfEIT) represents a promising biomedical imaging modality that enables the estimation of tissue conductivities across a range of frequencies. Addressing this challenge, we present a novel variational network, a model-based learning paradigm that strategically merges the advantages and interpretability of classical iterative reconstruction with the power of deep learning. This approach integrates graph neural networks (GNNs) within the iterative Proximal Regularized Gauss Newton (PRGN) framework. By unfolding the PRGN algorithm, where each iteration corresponds to a network layer, we leverage the physical insights of nonlinear model fitting alongside the GNN’s capacity to capture inter-frequency correlations. Notably, the GNN architecture preserves the irregular triangular mesh structure used in the solution of the nonlinear forward model, enabling accurate reconstruction of overlapping tissue fraction concentrations.

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Publication Details

Journal
Journal of Computational Physics
Published
2026-08-19
DOI
https://doi.org/10.1016/j.jcp.2026.115293
Primary Topic
Electrical and Bioimpedance Tomography
Type
article
Field-Weighted Citation Impact
0.00

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article

Nonlinear multi-frequency electrical impedance tomography: An unfolded optimization approach

Matteo Santacesaria, Damiana Lazzaro, Serena Morigi, Luca Ratti et al.
Journal of Computational Physics
Electrical and Bioimpedance Tomography
article

Nonlinear multi-frequency electrical impedance tomography: An unfolded optimization approach

Matteo Santacesaria, Damiana Lazzaro, Serena Morigi, Luca Ratti, Giovanni S. Alberti
article en

Abstract

Multi-frequency Electrical Impedance Tomography (mfEIT) represents a promising biomedical imaging modality that enables the estimation of tissue conductivities across a range of frequencies. Addressing this challenge, we present a novel variational network, a model-based learning paradigm that strategically merges the advantages and interpretability of classical iterative reconstruction with the power of deep learning. This approach integrates graph neural networks (GNNs) within the iterative Proximal Regularized Gauss Newton (PRGN) framework. By unfolding the PRGN algorithm, where each iteration corresponds to a network layer, we leverage the physical insights of nonlinear model fitting alongside the GNN’s capacity to capture inter-frequency correlations. Notably, the GNN architecture preserves the irregular triangular mesh structure used in the solution of the nonlinear forward model, enabling accurate reconstruction of overlapping tissue fraction concentrations.

Journal of Computational PhysicsVol. 567
Istituto Nazionale di Fisica Nucleare, Sezione di Genova (IT), University of Genoa (IT), University of Bologna (IT)
European Research Council, Air Force Office of Scientific Research, Ministero dell'Istruzione e del Merito
Openalex Percentile: Top 19%
Electrical and Bioimpedance Tomography
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