Global Dynamics of a Non-Markovian Epidemic Model on Complex Networks

Abstract. In the early stages of a newly emerged or reemerged disease, there is a rapid increase in new infections, which can potentially lead to a healthcare crisis due to constraints of available medical resources. It is important to note that the recovery period of these emerging diseases typically follows a Gamma distribution rather than being narrowly centered around the mean. In this study, we propose a susceptible-infectious-recovered (SIR) network model that incorporates a general recovery rate and a saturation treatment function. We establish the well-posedness and global stability of the disease-free equilibrium in the model by employing semigroup theory and the standard comparison principle, respectively. From an epidemiological perspective, when the delayed treatment effect exceeds a significant threshold, a phenomenon known as backward bifurcation emerges near the disease-free equilibrium. This assertion is supported by an updated version of the Lyapunov–Schmidt approach. Additionally, we conduct numerical simulations to investigate how network topology and non-Markovian processes affect the patterns of disease transmission.

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Publication Details

Journal
SIAM Journal on Applied Mathematics
Published
2026-08-17
DOI
https://doi.org/10.1137/24m1711546
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Global Dynamics of a Non-Markovian Epidemic Model on Complex Networks

Gui‐Quan Sun, Maia Martcheva, Junyuan Yang, Jun Zhang
SIAM Journal on Applied Mathematics
COVID-19 epidemiological studies
article

Global Dynamics of a Non-Markovian Epidemic Model on Complex Networks

Gui‐Quan Sun, Maia Martcheva, Junyuan Yang, Jun Zhang
article en

Abstract

Abstract. In the early stages of a newly emerged or reemerged disease, there is a rapid increase in new infections, which can potentially lead to a healthcare crisis due to constraints of available medical resources. It is important to note that the recovery period of these emerging diseases typically follows a Gamma distribution rather than being narrowly centered around the mean. In this study, we propose a susceptible-infectious-recovered (SIR) network model that incorporates a general recovery rate and a saturation treatment function. We establish the well-posedness and global stability of the disease-free equilibrium in the model by employing semigroup theory and the standard comparison principle, respectively. From an epidemiological perspective, when the delayed treatment effect exceeds a significant threshold, a phenomenon known as backward bifurcation emerges near the disease-free equilibrium. This assertion is supported by an updated version of the Lyapunov–Schmidt approach. Additionally, we conduct numerical simulations to investigate how network topology and non-Markovian processes affect the patterns of disease transmission.

SIAM Journal on Applied MathematicsVol. 86(4)
Shanxi University (CN), New York University Shanghai (CN), University of Florida (US)
National Natural Science Foundation of China, Natural Science Foundation of Shanxi Province, China Scholarship Council
Good health and well-being
Openalex Percentile: Top 11%
COVID-19 epidemiological studies
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