Rhodium-Catalyzed <i>N</i> -Allylationof Sulfoximines Using Alkyl Alkynes
Abstract Rhodium-catalyzed N-allylation coupling reactions of sulfoximines with alkyl alkynes have been reported. The branched allylic products were obtained with a rhodium catalyst under mild reaction conditions and provided good to excellent yields of N-allylic sulfoximines. This protocol provides efficient access to diverse N-allylic sulfoximine derivatives, showing broad functional group compatibility and substantial substrate scope.
Authors
- Xiangyu Lin
- Wenbing Sheng (ORCID: https://orcid.org/0000-0002-9780-0033)
- Wei Wang (ORCID: https://orcid.org/0000-0003-0876-2205)
- Yangyang Li (ORCID: https://orcid.org/0009-0003-2578-856X)
- Yunxi Zhang
- Yang Zhang
- Jingmin Chen
- Caiyun Peng
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- ACS Omega
- Published
- 2026-08-17
- DOI
- https://doi.org/10.1021/acsomega.6c06998
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hunan Province
- Hunan University of Chinese Medicine