Two-Year-Old Girl With Chronic Cough and Lymphadenopathy

A 27-month-old previously healthy girl presented with 3 months of cough and 1 day of fever and rhinorrhea. Her parents had immigrated from Africa, but our patient had been born in the United States and had no notable environmental exposures. An alarming chest radiograph suggested a broad differential diagnosis, and lung biopsy with pathology was ultimately required to confirm her rare diagnosis. Both her diagnosis and its significant implications are discussed.

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Publication Details

Journal
PEDIATRICS
Published
2026-08-18
DOI
https://doi.org/10.1542/peds.2025-074436
Primary Topic
Lymphadenopathy Diagnosis and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Two-Year-Old Girl With Chronic Cough and Lymphadenopathy

Elizabeth D. Lowenthal, Richard Rutstein, Lisa N. Akhtar
PEDIATRICS
Lymphadenopathy Diagnosis and Analysis
article

Two-Year-Old Girl With Chronic Cough and Lymphadenopathy

Elizabeth D. Lowenthal, Richard Rutstein, Lisa N. Akhtar
article en

Abstract

A 27-month-old previously healthy girl presented with 3 months of cough and 1 day of fever and rhinorrhea. Her parents had immigrated from Africa, but our patient had been born in the United States and had no notable environmental exposures. An alarming chest radiograph suggested a broad differential diagnosis, and lung biopsy with pathology was ultimately required to confirm her rare diagnosis. Both her diagnosis and its significant implications are discussed.

PEDIATRICS
Northwestern University (US), Children's Hospital of Philadelphia (US), Lurie Children's Hospital (US)
Openalex Percentile: Top 8%
Lymphadenopathy Diagnosis and Analysis
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