Recurrent multiple giant cystic-solid hemangioblastomas of the cerebellopontine angle with extension to both cerebellar hemispheres: a case report and literature review
Multiple giant cystic-solid hemangioblastomas arising in the cerebellopontine angle (CPA) and extending to both cerebellar hemispheres are exceedingly uncommon. We report the case of a 54-year-old female patient who was admitted with to the hospital with a two-month history of headache and hearing loss. On physical examination, the patient was alert, and Romberg’s sign was positive. Magnetic resonance imaging (MRI) revealed the presence of multiple irregular cystic-solid abnormal signal shadows in the right CPA and bilateral cerebellar hemispheres. Total tumor resection was performed via a midline suboccipital approach, resulting in marked relief of the patient’s headache symptoms and preservation of cranial nerve function. The diagnosis of hemangioblastoma was confirmed by postoperative immunohistochemical staining.
Authors
- Zihao Wang (ORCID: https://orcid.org/0000-0002-3961-0100)
- Xiaochao Xia (ORCID: https://orcid.org/0009-0005-0591-2396)
- Shixue Xia
- Lvmeng Song
- Yinchuan Cheng
- Ping Xiong (ORCID: https://orcid.org/0009-0008-4076-4896)
- Shun Li (ORCID: https://orcid.org/0009-0004-9380-1508)
- Shumin Wang
- Jike Amu
- Xia Wu
Institutions
- The First People's Hospital of Shunde (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- First People's Hospital of Chongqing (CN)
- Gaozhou People's Hospital (CN)
- Xiang Yang No.1 People's Hospital (CN)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2026-08-17
- DOI
- https://doi.org/10.1186/s13000-026-01840-5
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00