Rare variant of Zinner syndrome with ectopic seminal vesicle and prostatic hypoplasia: A case report

Zinner syndrome is a rare congenital malformation of the male genitourinary tract characterized by the classic triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction, resulting from abnormal development of the mesonephric (Wolffian) duct during embryogenesis. We report a case of a 30-year-old man presenting with ejaculatory dysfunction. Ultrasound and pelvic magnetic resonance imaging (MRI) revealed left renal agenesis, a multilocular retrovesical cystic lesion highly suggestive of an ectopic left seminal vesicle, and prostatic hypoplasia. These findings suggest an unusual spectrum of mesonephric duct developmental anomalies related to Zinner syndrome and highlight the diagnostic value of MRI.

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Publication Details

Journal
Radiology Case Reports
Published
2026-08-14
DOI
https://doi.org/10.1016/j.radcr.2026.07.021
Primary Topic
Urologic and reproductive health conditions
Type
article
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article

Rare variant of Zinner syndrome with ectopic seminal vesicle and prostatic hypoplasia: A case report

T. Nguyen, Xuan Bien Doan, Huy Ho, Thi Tinh Tam Tran
Radiology Case Reports
Urologic and reproductive health conditions
article

Rare variant of Zinner syndrome with ectopic seminal vesicle and prostatic hypoplasia: A case report

T. Nguyen, Xuan Bien Doan, Huy Ho, Thi Tinh Tam Tran
article en

Abstract

Zinner syndrome is a rare congenital malformation of the male genitourinary tract characterized by the classic triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction, resulting from abnormal development of the mesonephric (Wolffian) duct during embryogenesis. We report a case of a 30-year-old man presenting with ejaculatory dysfunction. Ultrasound and pelvic magnetic resonance imaging (MRI) revealed left renal agenesis, a multilocular retrovesical cystic lesion highly suggestive of an ectopic left seminal vesicle, and prostatic hypoplasia. These findings suggest an unusual spectrum of mesonephric duct developmental anomalies related to Zinner syndrome and highlight the diagnostic value of MRI.

Radiology Case ReportsVol. 21(11)
Da Nang Hospital (VN)
Good health and well-being
Openalex Percentile: Top 8%
Urologic and reproductive health conditions
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