Health-related quality of life and associated multimorbidity patterns among adults in rural northern China: a cross-sectional study

Among rural adults aged ≥ 30 years in Shanxi Province, China, 37.05% had multimorbidity. Compared with participants without multimorbidity, they had lower health utility (0.94 vs. 1.00) and more frequent HRQoL impairment (63.69% vs. 32.80%). Age ≥ 60 years was negatively associated with HRQoL, whereas higher education, annual income ≥ 20,000 yuan, high alcohol consumption, and high-intensity physical activity were positively associated with HRQoL. Pain/discomfort was the most frequently affected dimension (56.48%). Dementia had the lowest utility index among individual conditions (0.78), and patterns involving pain or functional impairment, such as arthritis and stroke, showed the greatest HRQoL burden. These results have potential implications for public health strategies aimed at managing the clustering of multiple chronic conditions with high burden—especially those with pain and functional limitations—over single prevalent conditions to maximise health gains in resource-limited rural settings.

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Journal
Scientific Reports
Published
2026-08-14
DOI
https://doi.org/10.1038/s41598-026-66082-3
Primary Topic
Chronic Disease Management Strategies
Type
article
Field-Weighted Citation Impact
0.00

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article

Health-related quality of life and associated multimorbidity patterns among adults in rural northern China: a cross-sectional study

Tianyou Hao, Runlan Li, Maoyi Tian, Zhifang Li et al.
Scientific Reports
Chronic Disease Management Strategies
article

Health-related quality of life and associated multimorbidity patterns among adults in rural northern China: a cross-sectional study

Tianyou Hao, Runlan Li, Maoyi Tian, Zhifang Li, Siyuan Feng, Xiangxian Feng, Yanxing Li, Ronglong Li, Hongmei Yang, Shuai Tang, Xinyi Zhang
article en

Abstract

Among rural adults aged ≥ 30 years in Shanxi Province, China, 37.05% had multimorbidity. Compared with participants without multimorbidity, they had lower health utility (0.94 vs. 1.00) and more frequent HRQoL impairment (63.69% vs. 32.80%). Age ≥ 60 years was negatively associated with HRQoL, whereas higher education, annual income ≥ 20,000 yuan, high alcohol consumption, and high-intensity physical activity were positively associated with HRQoL. Pain/discomfort was the most frequently affected dimension (56.48%). Dementia had the lowest utility index among individual conditions (0.78), and patterns involving pain or functional impairment, such as arthritis and stroke, showed the greatest HRQoL burden. These results have potential implications for public health strategies aimed at managing the clustering of multiple chronic conditions with high burden—especially those with pain and functional limitations—over single prevalent conditions to maximise health gains in resource-limited rural settings.

Scientific Reports
Harbin Medical University (CN), Shanxi Medical University (CN), Changzhi Medical College (CN), Qinghai Institute for Endemic Diease Prevention and Control (CN), Xi’an International University (CN)
Harbin Medical University, National Natural Science Foundation of China
No poverty
Openalex Percentile: Top 9%
Chronic Disease Management Strategies
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Health-related quality of life and associated multimorbidity patterns among adults in rural northern China: a cross-sectional study — Tianyou Hao, Runlan Li, et al. · Scientific Reports (2026) | TGRS Research Map | TGRS