Successful Non-surgical Treatment for a Duodenal Perforation Caused by the Rupture of an Intraductal Papillary Mucinous Neoplasm of the Pancreas
An intraductal papillary mucinous neoplasm (IPMN) was incidentally detected in a 91-year-old woman 12 years before her current admission. The patient declined additional examinations and surgical intervention. Over the subsequent years, she experienced recurrent acute pancreatitis and ultimately developed a gastrointestinal perforation due to the rupture of the IPMN. Considering her age, general condition, and personal wishes, conservative management was selected, which allowed her to successfully resume oral intake until death from cancer. This rare clinical course provides valuable insights into the management of older adults with IPMN, a condition that is likely to be frequently encountered as the population ages.
Authors
- Keiichi Ito (ORCID: https://orcid.org/0000-0001-8524-2903)
- Hiroaki Koike (ORCID: https://orcid.org/0000-0002-6522-7682)
- Kohzoh Makita (ORCID: https://orcid.org/0000-0002-7857-3824)
- Akira Miyazaki
Institutions
- Nerima General Hospital (JP)
- Nikko Memorial Hospital (JP)
- Midorigaoka Hospital (JP)
Publication Details
- Journal
- Internal Medicine
- Published
- 2026-08-14
- DOI
- https://doi.org/10.2169/internalmedicine.6315-25
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00