Early First-Trimester Diagnosis of Thoracopagus Conjoined Twins with a Shared Cardiac Structure

Thoracopagus conjoined twins are the most common type of conjoined twinning and are frequently associated with shared cardiac anatomy, the principal determinant of prognosis and postnatal survival. Early prenatal diagnosis is essential for accurate counseling and timely pregnancy management. We report the diagnosis of thoracopagus conjoined twins with a shared cardiac structure in a 35-year-old primigravid woman at 8 weeks and 3 days of gestation. High-resolution transvaginal ultrasound demonstrated persistent thoracic fusion, fixed relative fetal position, a single yolk sac, a single umbilical cord, and absence of an intertwin membrane. Color Doppler confirmed a single sonographically detectable cardiac complex, while three-dimensional ultrasound enhanced spatial visualization and facilitated parental counseling. Differential diagnoses, including monochorionic twins with close apposition, TRAP sequence, body stalk anomaly, and other forms of conjoined twinning, were systematically excluded. Early first-trimester recognition of thoracopagus conjoined twins with shared cardiac anatomy is feasible using dynamic ultrasound and Doppler imaging. Establishing the diagnosis before the end of the first trimester enables accurate prognostic assessment, timely multidisciplinary counseling, and informed parental decision-making for this condition associated with an extremely poor prognosis.

Authors

Institutions

Publication Details

Journal
Diagnostics
Published
2026-08-14
DOI
https://doi.org/10.3390/diagnostics16162562
Primary Topic
Assisted Reproductive Technology and Twin Pregnancy
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Early First-Trimester Diagnosis of Thoracopagus Conjoined Twins with a Shared Cardiac Structure

Adelina Staicu, Georgiana Nemeti, Dan Boitor‐Borza, Camelia Albu et al.
Diagnostics
Assisted Reproductive Technology and Twin Pregnancy
article

Early First-Trimester Diagnosis of Thoracopagus Conjoined Twins with a Shared Cardiac Structure

Adelina Staicu, Georgiana Nemeti, Dan Boitor‐Borza, Camelia Albu, Daniel Mureșan, Gheorghe Cruciat, Iulian Goidescu, Ioana Cristina Rotar, Mihai Surcel, Andreea Florian, Roxana Constantin
article en

Abstract

Thoracopagus conjoined twins are the most common type of conjoined twinning and are frequently associated with shared cardiac anatomy, the principal determinant of prognosis and postnatal survival. Early prenatal diagnosis is essential for accurate counseling and timely pregnancy management. We report the diagnosis of thoracopagus conjoined twins with a shared cardiac structure in a 35-year-old primigravid woman at 8 weeks and 3 days of gestation. High-resolution transvaginal ultrasound demonstrated persistent thoracic fusion, fixed relative fetal position, a single yolk sac, a single umbilical cord, and absence of an intertwin membrane. Color Doppler confirmed a single sonographically detectable cardiac complex, while three-dimensional ultrasound enhanced spatial visualization and facilitated parental counseling. Differential diagnoses, including monochorionic twins with close apposition, TRAP sequence, body stalk anomaly, and other forms of conjoined twinning, were systematically excluded. Early first-trimester recognition of thoracopagus conjoined twins with shared cardiac anatomy is feasible using dynamic ultrasound and Doppler imaging. Establishing the diagnosis before the end of the first trimester enables accurate prognostic assessment, timely multidisciplinary counseling, and informed parental decision-making for this condition associated with an extremely poor prognosis.

DiagnosticsVol. 16(16)
Iuliu Hațieganu University of Medicine and Pharmacy (RO), Clinical Emergency Hospital Bucharest (RO)
Good health and well-being
Openalex Percentile: Top 6%
Assisted Reproductive Technology and Twin Pregnancy
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.