Geometry‐Related Technical Complications After <scp>LVAD</scp> Implantation: Impact on Device Dysfunction and Clinical Outcomes
BACKGROUND: Geometry of LVAD implantation is a determinant of pump performance and hemocompatibility. Despite technically successful operations, avoidable geometric errors may produce characteristic imaging patterns and clinically relevant device dysfunction. OBJECTIVES: To determine the frequency, diagnostic pathway, and clinical impact of preventable geometry-related failure modes after HeartMate 3 implantation in a single-center referral cohort, specifically inflow cannula malposition, outflow graft kinking/excessive length, and aortic anastomotic stenosis. METHODS: Retrospective, single-center analysis of 21 consecutive HeartMate 3 recipients implanted between 2016 and 2025 at external centers and subsequently evaluated in our department. All patients underwent CT/CTA when device dysfunction was suspected. Failure modes were predefined and adjudicated using standardized imaging criteria. CT/CTA was the primary modality used to confirm geometric failure modes following triggers such as low-flow alarms, hemolysis, and abnormal chest radiography. RESULTS: Among 21 HeartMate 3 recipients, inflow cannula malposition was identified in 7 patients, outflow graft kinking/excessive length in 12, and aortic anastomotic stenosis in 2. CONCLUSIONS: In this single-center referral cohort, geometric failure modes were identified in 15 of 21 patients (71.4%) after HeartMate 3 implantation and showed reproducible CT/CTA signatures. A standardized imaging-driven diagnostic pathway may improve recognition of correctable geometric problems in patients referred for suspected device dysfunction; given the referral-based design, these frequencies should not be interpreted as the true incidence in an unselected HeartMate 3 population.
Authors
- Saeed Torabi (ORCID: https://orcid.org/0000-0003-0646-0465)
- Sara Knigge (ORCID: https://orcid.org/0000-0001-7571-3775)
- Zurab Darbaidze
- Alina Zubarevich (ORCID: https://orcid.org/0000-0002-2444-5747)
- Christian D. Etz (ORCID: https://orcid.org/0000-0002-8224-2390)
- Ali Saad Merzah (ORCID: https://orcid.org/0000-0002-7774-5065)
- Mohamad Dia
- Borys M. Todurov (ORCID: https://orcid.org/0009-0000-2047-4447)
- Josephina Haunschild (ORCID: https://orcid.org/0000-0003-1742-5841)
- Güneş Doğan (ORCID: https://orcid.org/0000-0002-5984-9426)
- S. Chaikovska (ORCID: https://orcid.org/0000-0001-9847-7760)
- Jasmin S. Hanke (ORCID: https://orcid.org/0000-0002-1434-6905)
- Ezin Deniz (ORCID: https://orcid.org/0009-0009-8703-7140)
- Max BIEWER
- Arjang Ruhparwar
- Alexander Weymann
- Jan D. Schmitto
- Bastian Schmack
Institutions
- Medizinische Hochschule Hannover (DE)
- Sana Kliniken Duisburg (DE)
- Stadtwerke Duisburg (Germany) (DE)
- BG Klinikum Duisburg (DE)
- Kyiv City Clinical Oncology Center (UA)
- University Hospital Cologne (DE)
- University of Rostock (DE)
Publication Details
- Journal
- Artificial Organs
- Published
- 2026-08-13
- DOI
- https://doi.org/10.1111/aor.70204
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00