Geometry‐Related Technical Complications After <scp>LVAD</scp> Implantation: Impact on Device Dysfunction and Clinical Outcomes

BACKGROUND: Geometry of LVAD implantation is a determinant of pump performance and hemocompatibility. Despite technically successful operations, avoidable geometric errors may produce characteristic imaging patterns and clinically relevant device dysfunction. OBJECTIVES: To determine the frequency, diagnostic pathway, and clinical impact of preventable geometry-related failure modes after HeartMate 3 implantation in a single-center referral cohort, specifically inflow cannula malposition, outflow graft kinking/excessive length, and aortic anastomotic stenosis. METHODS: Retrospective, single-center analysis of 21 consecutive HeartMate 3 recipients implanted between 2016 and 2025 at external centers and subsequently evaluated in our department. All patients underwent CT/CTA when device dysfunction was suspected. Failure modes were predefined and adjudicated using standardized imaging criteria. CT/CTA was the primary modality used to confirm geometric failure modes following triggers such as low-flow alarms, hemolysis, and abnormal chest radiography. RESULTS: Among 21 HeartMate 3 recipients, inflow cannula malposition was identified in 7 patients, outflow graft kinking/excessive length in 12, and aortic anastomotic stenosis in 2. CONCLUSIONS: In this single-center referral cohort, geometric failure modes were identified in 15 of 21 patients (71.4%) after HeartMate 3 implantation and showed reproducible CT/CTA signatures. A standardized imaging-driven diagnostic pathway may improve recognition of correctable geometric problems in patients referred for suspected device dysfunction; given the referral-based design, these frequencies should not be interpreted as the true incidence in an unselected HeartMate 3 population.

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Publication Details

Journal
Artificial Organs
Published
2026-08-13
DOI
https://doi.org/10.1111/aor.70204
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Geometry‐Related Technical Complications After LVAD Implantation: Impact on Device Dysfunction and Clinical Outcomes

Saeed Torabi, Sara Knigge, Zurab Darbaidze, Alina Zubarevich et al.
Artificial Organs
Mechanical Circulatory Support Devices
article

Geometry‐Related Technical Complications After LVAD Implantation: Impact on Device Dysfunction and Clinical Outcomes

Saeed Torabi, Sara Knigge, Zurab Darbaidze, Alina Zubarevich, Christian D. Etz, Ali Saad Merzah, Mohamad Dia, Borys M. Todurov, Josephina Haunschild, Güneş Doğan, S. Chaikovska, Jasmin S. Hanke, Ezin Deniz, Max BIEWER, Arjang Ruhparwar, Alexander Weymann, Jan D. Schmitto, Bastian Schmack
article en

Abstract

BACKGROUND: Geometry of LVAD implantation is a determinant of pump performance and hemocompatibility. Despite technically successful operations, avoidable geometric errors may produce characteristic imaging patterns and clinically relevant device dysfunction. OBJECTIVES: To determine the frequency, diagnostic pathway, and clinical impact of preventable geometry-related failure modes after HeartMate 3 implantation in a single-center referral cohort, specifically inflow cannula malposition, outflow graft kinking/excessive length, and aortic anastomotic stenosis. METHODS: Retrospective, single-center analysis of 21 consecutive HeartMate 3 recipients implanted between 2016 and 2025 at external centers and subsequently evaluated in our department. All patients underwent CT/CTA when device dysfunction was suspected. Failure modes were predefined and adjudicated using standardized imaging criteria. CT/CTA was the primary modality used to confirm geometric failure modes following triggers such as low-flow alarms, hemolysis, and abnormal chest radiography. RESULTS: Among 21 HeartMate 3 recipients, inflow cannula malposition was identified in 7 patients, outflow graft kinking/excessive length in 12, and aortic anastomotic stenosis in 2. CONCLUSIONS: In this single-center referral cohort, geometric failure modes were identified in 15 of 21 patients (71.4%) after HeartMate 3 implantation and showed reproducible CT/CTA signatures. A standardized imaging-driven diagnostic pathway may improve recognition of correctable geometric problems in patients referred for suspected device dysfunction; given the referral-based design, these frequencies should not be interpreted as the true incidence in an unselected HeartMate 3 population.

Artificial Organs
Medizinische Hochschule Hannover (DE), Sana Kliniken Duisburg (DE), Stadtwerke Duisburg (Germany) (DE), BG Klinikum Duisburg (DE), Kyiv City Clinical Oncology Center (UA), University Hospital Cologne (DE), University of Rostock (DE)
Good health and well-being
Openalex Percentile: Top 18%
Mechanical Circulatory Support Devices
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