HPV-associated Oropharyngeal Squamous Cell Carcinoma: An Imaging Framework for AJCC Version 9 TNM Staging
The American Joint Committee on Cancer/ Union for International Cancer Control version 9 TNM staging system for human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma provides an updated framework for radiology reporting, incorporating cautious assessment of unequivocal imaging-detected extranodal extension and acknowledging the emerging, complementary role of circulating tumor tissue–modified viral HPV DNA in surveillance.
Authors
- Pranjal Rai (ORCID: https://orcid.org/0009-0008-3796-8273)
- Alok A. Bhatt (ORCID: https://orcid.org/0000-0003-3400-7123)
- Adam L. Holtzman (ORCID: https://orcid.org/0000-0002-1412-7155)
Institutions
- Mayo Clinic (US)
- Jacksonville College (US)
- WinnMed (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Radiology Imaging Cancer
- Published
- 2026-08-14
- DOI
- https://doi.org/10.1148/rycan.260013
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00