A little-known perspective on the I-squared statistic
The I-squared statistic has become hugely popular in meta-analysis. Motivated by the recent statement that 'Informally, it can be considered to reflect the extent to which confidence intervals displayed in a forest plot do not overlap with each other', this short note formalises this perspective. The insights provided by our analysis lend further weight to the interpretation of the I-squared statistic as a measure of inconsistency. This perspective reminds us that visual inspections of forest plots are vitally important when assessing between-study variation.
Authors
- Julian P. T. Higgins (ORCID: https://orcid.org/0000-0002-8323-2514)
- Dan Jackson (ORCID: https://orcid.org/0000-0002-4963-8123)
- José A López-López (ORCID: https://orcid.org/0000-0002-9655-3616)
Institutions
- AstraZeneca (United Kingdom) (GB)
- University of Bristol (GB)
- Universidad de Murcia (ES)
Publication Details
- Journal
- Research Synthesis Methods
- Published
- 2026-11-03
- DOI
- https://doi.org/10.1017/rsm.2026.10125
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.00