Oximophosphinothiolationof Alkenes with Sodium Nitrite,Elemental Sulfur, and Secondary Arylphosphines
Abstract A simple and efficient oximophosphinothiolation of alkenes with sodium nitrite, elemental sulfur, and secondary arylphosphines has been developed. This transformation can be carried out under mild and additive-free conditions, employing NaNO2 and S8 as the NO source and sulfur source, respectively. A wide variety of α-dithiophosphinate oximes could be accessed via this method in moderate to good yields, and the reaction showed good tolerance to diverse functional groups.
Authors
- Linghao Ran
- Huilan Yue (ORCID: https://orcid.org/0000-0003-4457-3233)
- Wei Wei (ORCID: https://orcid.org/0000-0002-0015-7636)
- Yingjie Wang (ORCID: https://orcid.org/0000-0002-6642-8726)
- Yanan Hou
- Xi Li
- Yuluan Jin
- Dong Yi
Institutions
- Changsha Medical University (CN)
- Nanjing Forestry University (CN)
- Qufu Normal University (CN)
- Southwest Medical University (CN)
- Northwest Institute of Mechanical and Electrical Engineering (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-08-13
- DOI
- https://doi.org/10.1021/acs.joc.6c01493
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province